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J Pediatr Infect Dis 2022; 17(01): 053-058
DOI: 10.1055/s-0041-1739393
Case Report

The First Case of Multisystem Inflammatory Syndrome in Children Successfully Treated with Combined Therapies Including Extracorporeal Membrane Oxygenation and Plasmapheresis

Capan Konca 
1   Department of Pediatrics, Division of Pediatric Intensive Care Unit, Tepecik Training and Research Hospital, Izmir, Turkey
,
Ayse B. Anil
2   Pediatric Intensive Care Department, School of Medicine, Izmir Katip Celebi University, Izmir, Turkey
,
Onur Isik
3   Department of Congenital Heart Surgery, Tepecik Training and Research Hospital, Izmir, Turkey
,
Emine P. Kulluoglu
1   Department of Pediatrics, Division of Pediatric Intensive Care Unit, Tepecik Training and Research Hospital, Izmir, Turkey
,
Doga Luleyap
1   Department of Pediatrics, Division of Pediatric Intensive Care Unit, Tepecik Training and Research Hospital, Izmir, Turkey
,
Aysenur O. Dogruoz
1   Department of Pediatrics, Division of Pediatric Intensive Care Unit, Tepecik Training and Research Hospital, Izmir, Turkey
,
Muhammed Akyuz
3   Department of Congenital Heart Surgery, Tepecik Training and Research Hospital, Izmir, Turkey
,
Ilker Mercan
3   Department of Congenital Heart Surgery, Tepecik Training and Research Hospital, Izmir, Turkey
,
Ali R. Bakiler
4   Department of Pediatric Cardiology, Tepecik Training and Research Hospital, Izmir, Turkey
,
Fatih Durak
2   Pediatric Intensive Care Department, School of Medicine, Izmir Katip Celebi University, Izmir, Turkey
,
Belde K. Demir
5   Department of Pediatric Rheumatology, Tepecik Training and Research Hospital, Izmir, Turkey
,
Eda Oncel
6   Department of Pediatric Infectious Diseases, Tepecik Training and Research Hospital, Izmir, Turkey
› Author Affiliations Funding None.
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Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a severe disease that can lead to death. There is no definitive treatment for MIS-C yet. It has been reported that intravenous immunoglobulin, intravenous methylprednisolone, fluid supplements, antibiotics, inotropics, extracorporeal membrane oxygenation (ECMO), plasmapheresis, biological therapy, and anticoagulation therapy can be used for treatment. In this article, we presented an 8-year-old girl child patient who survived due to timely administered ECMO and combined therapies including plasmapheresis without any sequela despite her life-threatening condition due to MIS-C.

Keywords

Multisystem inflammatory syndrome in children - pediatric intensive care - ECMO - anakinra - plasmapheresis

Authors' Contributions

 • Literature search: C.K., A.B.A., D.L., and E.P.K.


 • Study design: C.K., A.B.A., F.D., and A.O.D.


 • Manuscript preparation: C.K. and A.B.A.


 • Review of manuscript: C.K. and A.B.A.


 • Contribute to management: O.I., M.A., I.M., A.R.B., B.K.D., and E.O.




Publication History

Received: 23 April 2021

Accepted: 24 August 2021

Article published online:
26 November 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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