J Neurol Surg A Cent Eur Neurosurg 2023; 84(04): 394-398
DOI: 10.1055/s-0041-1739229
Case Report

Cranial and Spinal Metastasis of a Nonfunctioning Pituitary Adenoma: Report of a Case

1   Department of Neurosurgery, University Hospital Halle, Halle, Germany
,
Christian Mawrin
2   Institut fuer Neuropathologie, Otto-von-Guericke-Universitaet, Magdeburg, Germany
,
Christian Strauss
3   Department of Neurosurgery, University of Halle-Wittenberg, Halle (Saale), Germany
,
Julian Prell
3   Department of Neurosurgery, University of Halle-Wittenberg, Halle (Saale), Germany
› Author Affiliations

Abstract

Pituitary carcinoma is a rare disease with surgical, radiotherapeutic, and chemotherapeutic treatment options. We present the case of a female patient diagnosed with a nonfunctioning pituitary adenoma who underwent several surgical procedures, radiations, and chemotherapeutic treatments with various substances. Sixteen years after the first diagnosis, a cranial and spinal metastatic spread of the tumor occurred. We opted for an individual therapy based on anecdotal evidence. Unfortunately, the recommended off-label treatment with a somatostatin analog substance was never given due to bureaucratic delays. This case report is about the challenging aspects of individual decision-making in rare neurosurgical diseases.



Publication History

Received: 29 October 2020

Accepted: 23 April 2021

Article published online:
02 December 2021

© 2021. Thieme. All rights reserved.

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