Planta Med 2021; 87(15): 1289
DOI: 10.1055/s-0041-1736907
Abstracts
8. Poster Contributions
8.8 Medicinal plants and natural product research on Traditional Medicines

Determination of anti-tyrosinase activity of acetone extracts from selected Potentilla L. species.

Autoren

  • D Augustynowicz

    1   Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, ul. Mickiewicza 2a, 15-230 Białystok, Poland

  • K Jakimiuk

    1   Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, ul. Mickiewicza 2a, 15-230 Białystok, Poland

  • J W Strawa

    1   Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, ul. Mickiewicza 2a, 15-230 Białystok, Poland

  • M Tomczyk

    1   Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, ul. Mickiewicza 2a, 15-230 Białystok, Poland

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Weitere Informationen
Auch verfügbar auf
 

Potentilla L. species (Rosaceae) have a long history of use since antiquity to treat diarrhoea, skin infections and inflammations in the mouth and throat. However, the literature reports that the genus Potentilla represents also a rich source of the monomeric and oligomeric flavan-3-ols [1] [2]. Thus, the present investigation aimed to assess the composition of the secondary metabolites of acetone extracts from aerial parts of selected Potentilla species using LC-MS/TOF analysis. Furthermore, the assessment of the anti-tyrosinase activity was performed. The acetone extracts from aerial parts of P. argentea (PAr), P. recta (PRe), P. grandiflora (PGr), P. norvergica (PN) and P. rupestris (PRu) have been obtained. LC-MS/TOF analysis demonstrated the presence of catechin and epicatechin and their derivatives. The most potent anti-tyrosinase activity exerted PAr and PN with IC50 of 262.3±0.285 and 309.1±1.502 µg/mL. The results allow us to conclude that the application of Potentilla species may be effective in treating diseases with the hyperactivity of tyrosinase.



Publikationsverlauf

Artikel online veröffentlicht:
13. Dezember 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart, Germany