Planta Med 2021; 87(15): 1252
DOI: 10.1055/s-0041-1736788
Abstracts
4. Young Researchers Workshop

Evaluation of endophytes on Albizia julibrissin DURAZZ. from wild collection

P Raab
1   Institute of Pharmaceutical Sciences, University of Graz, Austria
,
D Feiertag
2   Institute of Plant Sciences, University of Graz, Austria,
,
H Liang
3   State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, China
,
P F Tu
3   State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, China
,
M Grube
2   Institute of Plant Sciences, University of Graz, Austria,
,
R Bauer
1   Institute of Pharmaceutical Sciences, University of Graz, Austria
› Institutsangaben
Field research of Raab P. was funded by OeAD Marietta Blau-Stipendium
› Weitere Informationen
Auch verfügbar auf
 

The aim of our research is to discover new, plant-based alternatives for the treatment of chronic inflammatory diseases, from the treasures of traditional herbal medicines. [1] The bark extracts of Albizia julibrissin Durazz., showed anti-inflammatory activity in LPS- and IFNγ- induced RAW 264.7 macrophages and BV2 microglia cells in a screening phase, however the active compounds have not yet been identified. It has been reported, that Albiziae cortex is usually covered in patches of lichen and in the last few years, several plant endophytes have drawn considerable attention as a source of biologically active compounds. [2] To identify possible endophytes of A. julibrissin bark and their potential influence on the anti-inflammatory activity of

Albiziae cortex, samples from wild collection were dissected, surface sterilized and incubated at 28°C on different growth media. [3] Hyphae from the primary inoculation were picked and transferred to new agar plates to obtain a pure culture, which was used for direct PCR. Blast analysis was done to assign endophyte strains. Phytochemical analysis of active constituents is currently in progress.



Publikationsverlauf

Artikel online veröffentlicht:
13. Dezember 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References

  • 1 Waltenberger, B. et al. 2016. Monatshefte für Chemie - Chemical Monthly, 147(3), pp. 479–491. doi:10.1007/s00706-015-1653-y.
    PubMed
  • 2 Rai, N. et al. 2021. Mycology, 12(3), pp. 139–159. doi:10.1080/21501203.2020.1870579
    PubMed
  • 3 Sharma, N. et al. 2018. Journal of Applied Microbiology, 125(1), pp. 111–120. doi:10.1111/jam.13764
    PubMed