Abstract
Sinonasal squamous cell carcinoma (SNSCC) is a rare and aggressive malignancy which
often presents at an advanced stage. The gold-standard treatment includes negative-margin
surgical resection plus adjuvant therapy. In cases of orbital invasion, surgery requires
orbital exenteration which can carry significant morbidity and result in decreased
quality of life. In selected patients, induction chemotherapy (IC) can allow for orbit
preservation without compromising oncologic outcomes. The available literature will
be briefly discussed.
Keywords
sinonasal squamous cell carcinoma - orbit preservation - orbital exenteration - induction
chemotherapy
