CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2021; 42(04): 380-384
DOI: 10.1055/s-0041-1735438
Brief Communication

Primary Renal Neuroblastoma Mimicking Wilms Tumor

Kanwaljeet Kaur
1   Division of Pediatric Oncology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
,
Jagdish Prasad Meena
1   Division of Pediatric Oncology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
,
Prasanth Sri
1   Division of Pediatric Oncology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
,
Aditya Kumar Gupta
1   Division of Pediatric Oncology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
,
Manisha Jana
2   Department of Radiology, All India Institute of Medical Sciences, New Delhi, India
,
Venkateswaran K. Iyer
3   Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
,
Rakesh Kumar
4   Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India
,
Rachna Seth
1   Division of Pediatric Oncology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
› Author Affiliations
Funding None.

Abstract

Neuroblastoma (NB) is the most common extracranial solid malignancy in children younger than 5 years of age. It is an aggressive malignancy with evidence of secondary metastasis at the time of the initial presentation. NB is rightly known as a great masquerader. Herein, we describe three children who presented with renal masses mimicked as Wilms tumor initially and later diagnosed as NB on biopsy. The response to therapy was not satisfactory in all three children. A higher level of awareness and early recognition is important for diagnosing and managing NB. We should rule out NB when there is a diagnostic dilemma before nephrectomy in these patients. Intrarenal NB should be considered with the combination of renal mass and hypertension with elevated catecholamines. The distinction between these two tumors is important since both malignancies have different therapeutic and prognostic implications.



Publication History

Article published online:
26 November 2021

© 2021. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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