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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2021; 31(02): 378-382
DOI: 10.1055/s-0041-1734347
Case Series

Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series

Rashmi Singh 
1   Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
,
Priyanka Naranje 
1   Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
,
Devasenathipathy Kandasamy 
1   Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
,
Manisha Jana
1   Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
,
Aditya K. Gupta 
2   Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
,
Prashant P. Ramateke
3   Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
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Abstract

Langerhans cell histiocytosis (LCH) is a common cause of multifocal lytic skeletal lesions in children. However, multifocal osseous tuberculosis can affect children and mimics LCH on imaging, especially in endemic regions. We report cases with atypical manifestations of multifocal osseous tuberculosis which were presumptively diagnosed as LCH. The findings of our series of cases suggest that on computed tomography (CT) irregular sclerotic margins, abscess formation, sclerosis of involved bone, and button sequestrum point toward a diagnosis of multifocal osseous tuberculosis, especially in endemic regions.

Keywords

button sequestrum - Langerhans’ cell histiocytosis - multifocal osseous tuberculosis - skull - tuberculosis - vertebra plana


Publikationsverlauf

Artikel online veröffentlicht:
27. Juli 2021

© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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