Role of Imaging in a Case of Toxoplasmosis Presenting as Generalized LymphadenopathyFunding None.
Toxoplasmosis is caused by Toxoplasma gondii an obligate protozoan intracellular parasite. The disease has variable prevalence globally and is usually asymptomatic. Pregnant and immunocompromised people are at risk of getting infected. Enlarged lymph nodes are the most frequently observed clinical form of Toxoplasma in humans, mostly affecting posterior cervical nodes. Other organs usually affected are the brain and eyes. We present a case of toxoplasmosis with generalized lymphadenopathy mimicking metastasis in a lady with a previous history of operated pancreatic neoplasm.
28. Juli 2021 (online)
© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India
- 1 Singh S, Munawwar A, Rao S, Mehta S, Hazarika NK. Serologic prevalence of Toxoplasma gondii in Indian women of child bearing age and effects of social and environmental factors. PLoS Negl Trop Dis 2014; 8 (03) e2737
- 2 Saxena S, Kumar S, Kharbanda J. Toxoplasmosis submandibular lymphadenitis: report of an unusual case with a brief review. J Oral Maxillofac Pathol 2018; 22 (01) 116-120
- 3 Ivanova K, Glatz K, Zippelius A, Nicolas G, Itin P. Acute toxoplasmosis mimicking melanoma metastases: review of conditions causing false-positive results on (18)F-FDG PET/CT. Dermatology 2012; 225 (04) 349-353
- 4 Ferrer R. Lymphadenopathy: differential diagnosis and evaluation. Am Fam Physician 1998; 58 (06) 1313-1320
- 5 Joshi AR, Basantani AS, Patel TC. Role of CT and MRI in abdominal tuberculosis. Curr Radiol Rep 2014; 2: 10
- 6 Burrill J, Williams CJ, Bain G, Conder G, Hine AL, Misra RR. Tuberculosis: a radiologic review. Radiographics 2007; 27 (05) 1255-1273
- 7 Manzella A, Borba-Filho P, D’Ippolito G, Farias M. Abdominal manifestations of lymphoma: spectrum of imaging features. ISRN Radiol 2013; 2013: 483069
- 8 Frampas E. Lymphomas: basic points that radiologists should know. Diagn Interv Imaging 2013; 94 (02) 131-144
- 9 Zhang G, Yang ZG, Yao J. et al. Differentiation between tuberculosis and leukemia in abdominal and pelvic lymph nodes: evaluation with contrast-enhanced multidetector computed tomography. Clinics (São Paulo 2015; 70 (03) 162-168
- 10 Kligerman SJ, Auerbach A, Franks TJ, Galvin JR. Castleman disease of the thorax: clinical, radiologic, and pathologic correlation: from the radiologic pathology archives. Radiographics 2016; 36 (05) 1309-1332
- 11 Ko SF, Hsieh MJ, Ng SH. et al. Imaging spectrum of Castleman’s disease. AJR Am J Roentgenol 2004; 182 (03) 769-775
- 12 Venkata R Ramanan, Pudhiavan A, Venkataramanan A. The “cluster of black pearls” sign of sarcoid lymphadenopathy: a new sign on thin-section contrast-enhanced multidetector CT. Clin Radiol 2017; 72 (09) 729-736
- 13 Pantel AR, Ackerman D, Lee SC, Mankoff DA, Gade TP. Imaging cancer metabolism: underlying biology and emerging strategies. J Nucl Med 2018; 59 (09) 1340-1349
- 14 Kitajima K, Suenaga Y, Minamikawa T. et al. Clinical significance of SUVmax in (18)F-FDG PET/CT scan for detecting nodal metastases in patients with oral squamous cell carcinoma. Springerplus 2015; 4 (01) 718
- 15 Yu C, Xia X, Qin C, Sun X, Zhang Y, Lan X. Is SUVmax helpful in the differential diagnosis of enlarged mediastinal lymph nodes? A pilot study. Contrast Media Mol Imaging 2018; 2018: 3417190
- 16 Chen S, Li X, Chen M, Yin Y, Li N, Li Y. Limited diagnostic value of Dual-Time-Point (18)F-FDG PET/CT imaging for classifying solitary pulmonary nodules in granuloma-endemic regions both at visual and quantitative analyses. Eur J Radiol 2016; 85 (10) 1744-1749
- 17 Dunay IR, Gajurel K, Dhakal R, Liesenfeld O, Montoya JG. Treatment of toxoplasmosis: historical perspective, animal models, and current clinical practice. Clin Microbiol Rev 2018; 31 (04) e00057-e17
- 18 Taila AK, Hingwe AS, Johnson LE. Toxoplasmosis in a patient who was immunocompetent: a case report. J Med Case Reports 2011; 5: 16