CC BY-NC-ND 4.0 · J Lab Physicians 2022; 14(01): 001-005
DOI: 10.1055/s-0041-1734015
Review Article

Impact of Serum Amylase Level in the Outcome of Acute Organophosphorus Poisoning: 2-Year Cross-Sectional Study at Rural Teaching Hospital

Aniket Patil
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
,
Sunil Kumar
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
,
Anil Inamdar
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
,
Sourya Acharya
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
,
Anil Wanjari
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
,
Shilpa Bawankule
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
,
Sachin Agrawal
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
,
Tushar Sontakke
1   Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India
› Author Affiliations

Abstract

Introduction Prompt recognition and aggressive management of acute intoxication due to organophosphorus poisoning are essential to minimize the morbidity and mortality. The present study was undertaken to know the prognosis and outcome of organophosphorus poisoning patients with the estimation of low-cost enzymes like the serum amylase level in a population with financial constraints.

Methods In this cross-sectional study, we had enrolled 100 cases that had a history of exposure to organophosphorus compounds, and the serum amylase level was measured in all the patients. We assessed the outcome of all the patients in the form of discharge, need of ventilators, intensive care unit stay, and death.

Results The mean serum amylase level in discharge patients was 335.40 ± 192.45, and in the patients who died it was 843.37 ± 22.60. It was significant to predict the outcome (t-value 7.07, p-value 0.0001, statistically significant).

Conclusion Serum amylase level shows significant correlation with clinical outcomes in organophosphorus poisoning.



Publication History

Article published online:
08 September 2021

© 2021. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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