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Neuropediatrics 2022; 53(01): 026-031
DOI: 10.1055/s-0041-1733985
Original Article

School-Age Outcome of Fetuses with Isolated Complete Septum Pellucidum Agenesis at Prenatal Magnetic Resonance Imaging

Andrea Righini 
1   Pediatric Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Milan, Italy
,
Giana Izzo
1   Pediatric Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Milan, Italy
,
Chiara Doneda
1   Pediatric Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Milan, Italy
,
Barbara Scelsa
2   Pediatric Neurology Department, Children's Hospital V. Buzzi, Milan, Italy
,
Cecilia Parazzini
1   Pediatric Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Milan, Italy
› Author Affiliations Funding Statement No funding was received for the present work.
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Abstract

Objective To the best of our knowledge, there have not been studies to address the issue of long-term follow-up of patients with prenatal diagnosis of isolated complete septum pellucidum agenesis (SPA). The aim of this study was to acquire information about the school-age outcome of such patients as a resource for counseling parents receiving this prenatal finding.

Methods From a large fetal magnetic resonance (MR) database, we selected only those cases with isolated complete SPA as confirmed by two senior pediatric neuroradiologists in consensus; we then gathered information from the parents of those children who had reached the school age.

Results None among the 12 cases (mean age at follow-up: 8.7 years, range: 6–13 year) of the resulting final cohort presented visual or stature deficits; only one required special teaching assistance in school. All other 11 children resulted without any notable academic issue.

Conclusion Our report may provide information of practical value about the school-age outcome of fetuses detected by prenatal MR imaging to carry isolated complete SPA.

Keywords

fetal MR imaging - prenatal diagnosis - septum pellucidum - fetal brain


Publication History

Received: 16 November 2020

Accepted: 04 January 2021

Article published online:
17 August 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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