CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2021; 42(02): 146-152
DOI: 10.1055/s-0041-1732856
Review Article

Nanotechnology in Oral Cancer Prevention and Therapeutics: A Literature Review

Ritwika Kumar
1  School of Materials Science and Nano Technology, Jadavpur University, Kolkata, West Bengal, India
Kunal Jha
2  Department of Public Health Dentistry, Kalinga Institute of Dental Sciences, KIIT University, BBSR, Bhubaneswar, Odisha, India
Diplina Barman
3  Private Dental Practitioner, Hooghly, West Bengal, India
› Author Affiliations
Funding This study is self-funded.


The concept of nanotechnology revolves around the delivery of nano particle incorporated drugs which are originally engineered technology. Nanoparticles are used for targeted delivery and controlled release of a curative agents. Nanotechnology is gaining importance and is likely to be routine element of regular dental clinics. Nanomaterials are being incorporated in toothpastes, mouth rinses for improved efficiencies. It has found its use in restorative dental materials, anti-cariogenic enamel surface polishing agents, implant materials, etc. Few nanoparticles possess antimicrobial propertiesand intercepts bacterial activity. Nano dentistry is cost-effectiveness and timesaving compared to other techniques. Nano particles have also been beneficial to annihilate drug resistance, prevention of metastasis or lesion recurrence by earmarking malignant stem cells. Remarkable achievements were made in using nanoparticles for detecting and treating multiple variety of malignancies including colon cancer, prostate cancer, lung cancer, breast cancer, head and neck cancer, etc. This review was made to highlight the various clinical applications of nanotechnology in the diagnosis and curative care for oral cancer.

Publication History

Publication Date:
06 August 2021 (online)

© 2021. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

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