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CC BY 4.0 · Eur J Dent 2022; 16(01): 109-114
DOI: 10.1055/s-0041-1731831
Original Article

Synthesis and Characterization of Antifungal Nanocomposite AgSiO2 Polymethyl Methacrylate

Mahmoud Sabouhi
1   Department of Prosthodontics, Dental Materials Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
,
Maryam Amini-Pozveh
2   Department of Prosthodontics Dentistry, Dental Materials Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
,
Farshad Bajoghli
3   Department of Prosthodontics, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
,
Hamid reza Dastjerd
4   Institute of Biomaterial of Tehran University, Tehran University of Medical Science, Tehran, Iran
,
Rasoul Mohammadi
5   Department of Medical Parasitology and Mycology, School of Medicine, Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
› Institutsangaben Funding This study was supported by Isfahan University of Medical Sciences (research grant 395333).
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Abstract

Objectives Polymethyl methacrylate as the most common material used in denture bases has some problems. The aim of this study was to introduce a new nanocomposite of PMMA to improve flexural strength and antifungal properties.

Materials and Methods In this experimental study, AgSiO2 nanoparticles were prepared, and their characteristics were confirmed by scanning electron microscope and energy dispersive spectroscopy techniques. Then the nanoparticles in the weight ratio of 0.1, 0.3, 0.5, and 0.7% were incorporated to heat-cured PMMA and the control group included no nanoparticles.

To measure the flexural strength before and after thermocycling three-point bending test was used. Eight samples per group with dimensions of 65 × 10 × 2.5 mm were used. Antifungal activity against Candida albicans (PTCC 5027) was investigated through colony count method. Statistical analysis was done by SPSS at significance level of p-value ≤0.05.

Results The mean flexural strength in groups 0.1, 0.3, and 0.7% was significantly higher than the control. After thermocycling flexural strength of the control group was significantly lower than 0.3 and 0.5% groups. As the concentration of nanoparticles increased the antifungal activity improved (p < 0.05).

Conclusion Addition of nanoparticles AgSiO2 improved flexural strength and antifungal characteristics of PMMA.

Keywords

antifungal - Candida albicans - colony count - nanocomposite - polymethyl methacrylate - strength


Publikationsverlauf

Artikel online veröffentlicht:
12. August 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

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  • References

  • 1 Krunić N, Kostić M, Anđelković M. Acrylic resins: still irreplaceable materials in prosthetic dentistry. Acta Stomatol Naissi 2007; 23 (56) 749-754
    Google Scholar
  • 2 Choudhary S. Complete denture fracture—a proposed classification system and its incidence in National Capital Region population: a survey. J Indian Prosthodont Soc 2019; 19 (04) 307-312
    CrossrefPubMedGoogle Scholar
  • 3 Rajesh P, Ganapathy D, Chaudhary M. Prevalence of complete denture fracture—a retrospective study. PalArch's J Archaeol Egypt 2020; 17 (07) 502-508
    Google Scholar
  • 4 Gendreau L, Loewy ZG. Epidemiology and etiology of denture stomatitis. J Prosthodont 2011; 20 (04) 251-260
    CrossrefPubMedGoogle Scholar
  • 5 Gonda T, Ikebe K, Dong J, Nokubi T. Effect of reinforcement on overdenture strain. J Dent Res 2007; 86 (07) 667-671
    CrossrefPubMedGoogle Scholar
  • 6 Gonda T, Maeda Y, Walton JN, MacEntee MI. Fracture incidence in mandibular overdentures retained by one or two implants. J Prosthet Dent 2010; 103 (03) 178-181
    CrossrefPubMedGoogle Scholar
  • 7 Hussain WA, Hashim FS. Effect of additives on impact strength of denture base resin. Iraqi J Sci 2017; 58 (2B) 860-867
    Google Scholar
  • 8 Demir H, Görler O, Doğan A, Ozden S. The assessment of impact properties of a denture base polymer reinforced with various fibbers. Int J Acad Res 2017; 9 (01) 15-19
    CrossrefGoogle Scholar
  • 9 Golbidi F, Pozveh MA. Flexural strength of polymethyl methacrylate repaired with fiberglass. J Dent (Tehran) 2017; 14 (04) 231-236
    Google Scholar
  • 10 Wang R, Kayacan R, Küçükeşmen C. Nanotubes/polymethyl methacrylate composite resins as denture base materials. In: Zhang M, Naik RR, Dai L, eds. Carbon Nanomaterials for Biomedical Applications Springer International 2016: 227-240
  • 11 Wang R, Tao J, Yu B, Dai L. Characterization of multiwalled carbon nanotube-polymethyl methacrylate composite resins as denture base materials. J Prosthet Dent 2014; 111 (04) 318-326
    CrossrefPubMedGoogle Scholar
  • 12 Ahmed MA, Ebrahim MI. Effect of zirconium oxide nano-fillers addition on the flexural strength, fracture toughness, and hardness of heat-polymerized acrylic resin. World J Nano Sci Eng 2014; 4: 50-57
    CrossrefGoogle Scholar
  • 13 Alnamel HA, Mudhaffer M. The effect of silicon di oxide nano-fillers reinforcement on some properties of heat cure polymethyl methacrylate denture base material. J Baghdad Coll Dent 2014; 26 (01) 32-36
    CrossrefGoogle Scholar
  • 14 Pan Y. et al Novel acrylic resin denture base with enhanced mechanical properties by the incorporation of PMMA-modified hydroxyapatite. Prog Nat Sci 2013; 23 (01) 89-93
    CrossrefGoogle Scholar
  • 15 Sasaki H, Hamanaka I, Takahashi Y, Kawaguchi T. Effect of long-term water immersion or thermal shock on mechanical properties of high-impact acrylic denture base resins. Dent Mater J 2016; 35 (02) 204-209
    CrossrefPubMedGoogle Scholar
  • 16 Takahashi Y, Hamanaka I, Shimizu H. Effect of thermal shock on mechanical properties of injection-molded thermoplastic denture base resins. Acta Odontol Scand 2012; 70 (04) 297-302
    CrossrefPubMedGoogle Scholar
  • 17 Kim JS, Kuk E, Yu KN. et al Antimicrobial effects of silver nanoparticles. Nanomedicine (Lond) 2007; 3 (01) 95-101
    CrossrefPubMedGoogle Scholar
  • 18 Dhanalekshmi KI, Meena KS. Comparison of antibacterial activities of Ag@TiO2 and Ag@SiO2 core-shell nanoparticles. Spectrochim Acta A Mol Biomol Spectrosc 2014; 128: 887-890
    CrossrefPubMedGoogle Scholar
  • 19 Musić S, Filipović-Vinceković N, Sekovanić L. Precipitation of amorphous SiO2 particles and their properties. Braz J Chem Eng 2011; 28 (01) 89-94
    CrossrefGoogle Scholar
  • 20 Han Q, Li G, Wang D. et al Synthesis of Ag-SiO2 composite nanospheres and their catalytic activity. Sci China Chem 2014; 57 (06) 881-887
    CrossrefGoogle Scholar
  • 21 Kim YH, Lee DK, Kang YS. Synthesis and characterization of Ag and Ag-SiO 2 nanoparticles. Colloids Surf A Physicochem Eng Asp 2005; 257: 273-276
    CrossrefGoogle Scholar
  • 22 Cierech M, Kolenda A, Grudniak AM. et al Significance of polymethylmethacrylate (PMMA) modification by zinc oxide nanoparticles for fungal biofilm formation. Int J Pharm 2016; 510 (01) 323-335
    CrossrefPubMedGoogle Scholar
  • 23 Chaijareenont P, Takahashi H, Nishiyama N, Arksornnukit M. Effect of different amounts of 3-methacryloxypropyltrimethoxysilane on the flexural properties and wear resistance of alumina reinforced PMMA. Dent Mater J 2012; 31 (04) 623-628
    CrossrefPubMedGoogle Scholar
  • 24 Lung CYK, Matinlinna JP. Aspects of silane coupling agents and surface conditioning in dentistry: an overview. Dent Mater 2012; 28 (05) 467-477
    CrossrefPubMedGoogle Scholar
  • 25 Debnath S, Wunder SL, McCool JI, Baran GR. Silane treatment effects on glass/resin interfacial shear strengths. Dent Mater 2003; 19 (05) 441-448
    CrossrefPubMedGoogle Scholar
  • 26 Khaled SM, Sui R, Charpentier PA, Rizkalla AS. Synthesis of TiO(2)-PMMA nanocomposite: using methacrylic acid as a coupling agent. Langmuir 2007; 23 (07) 3988-3995
    CrossrefPubMedGoogle Scholar