Abstract
Peripheral nerve injuries represent a considerable portion of chronic disability that
especially affects the younger population. Prerequisites of proper peripheral nerve
injury treatment include in-depth knowledge of the anatomy, pathophysiology, and options
in surgical reconstruction. Our greater appreciation of nerve healing mechanisms and
the development of different microsurgical techniques have significantly refined the
outcomes in treatment for the past four decades. This work reviews the peripheral
nerve regeneration process after an injury, provides an overview of various coaptation
methods, and compares other available treatments such as autologous nerve graft, acellular
nerve allograft, and synthetic nerve conduits. Furthermore, the formation of neuromas
as well as their latest treatment options are discussed.
Keywords
peripheral nerve - injury - repair - review