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CC BY-NC-ND 4.0 · J Lab Physicians 2021; 13(03): 219-223
DOI: 10.1055/s-0041-1730878
Original Article

Bisalbuminemia: A Pathologist’s Insight of an Uncommon Phenomenon

Gargi Kapatia
1   Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Monika Wadhwa
2   Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Pankaj Malhotra
2   Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Gaurav Prakash
1   Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Ritu Aggarwal
1   Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
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Abstract

Background The incidence of a bifid electrophoretic pattern in the albumin region on serum protein electrophoresis is an infrequent phenomenon. The availability of literature from India is scarce and is limited to case reports.

Objective The aim of the study is to analyze the frequency of bisalbuminemia in an Indian referral facility. The study delved into their clinical associations.

Material and Methods The retrospective case records of the patient from the departmental database were scrutinized. The study subjects were for an 8-year study period.

Results There were about 39,900 serum electrophoresis performed in an 8-year study period. A total of 40 cases of bisalbuminemia were detected. The incidence in our cohort was 0.01%.

Conclusion Bisalbuminemia, an overtly benign condition, is infrequent in Indian population although not rare. It is associated with several clinical disorders; however, the association seems to be plausibly coincidental.

Keywords

gel electrophoresis - albumin - serum protein electrophoresis


Publication History

Article published online:
16 June 2021

© 2021. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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