Download PDF
CC BY-NC-ND 4.0 · J Lab Physicians 2021; 13(02): 192-194
DOI: 10.1055/s-0041-1730847
Case Report

Pandoraea apista Bacteremia in a COVID-Positive Man: A Rare Coinfection Case Report from North India

Sweta Singh
1   Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Chinmoy Sahu 
1   Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Sangram Singh Patel
1   Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Atul Garg
1   Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Ujjala Ghoshal
1   Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
› Author Affiliations
› Further Information
   Permissions and Reprints

Abstract

Pandoraea apista is a novel gram-negative bacillus usually isolated from respiratory specimens of cystic fibrosis patients. Few cases of bacteremia have also been reported due to this rare pathogen. Emergence of multidrug-resistant isolates of this bacillus is of grave concern. Here, we report a very interesting and unusual case of Pandoraea apista bacteremia in a coronavirus disease (COVID)–positive elderly diabetic man suffering from pneumonia. Prompt isolation and antibiotic sensitivity testing guided the patient’s treatment and yielded favorable outcome. The need of automated methods for identification and sensitivity testing limits the reporting of this rare but important pathogen in hospital settings. Detailed research work and studies are needed in this direction to better understand this pathogen and its clinical manifestations for better patient outcome.

Keywords

Pandoraea apista - bacillus - cystic fibrosis - bacteremia - COVID - pneumonia


Publication History

Article published online:
28 June 2021

© 2021. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Coenye T, Falsen E, Hoste B. et al. Description of Pandoraea gen. nov. with Pandorae aapista sp. nov., Pandoraea pulmonicola sp. nov., Pandoraea pnomenusa sp. nov., Pandoraea sputorum sp. nov. and Pandoraea norimbergensis comb. nov. Int J SystEvolMicrobiol 2000; 50 (02) 887-899
    Google Scholar
  • 2 Ambrose M, Malley RC, Warren SJ. et al. Pandoraea pnomenusa isolated from an Australian patient with cystic fibrosis. Front Microbiol 2016; 7: 692
    CrossrefPubMedGoogle Scholar
  • 3 Jeong SE, Lee HJ, Jia B, Jeon CO. Pandoraea terrae sp. nov., isolated from forest soil, and emended description of the genus Pandoraea Coenye et al. 2000. Int J SystEvolMicrobiol 2016; 66 (09) 3524-3530
    Google Scholar
  • 4 Feng Y, Ling Y, Bai T. et al. COVID-19 with different severities: a multicenter study of clinical features. Am J RespirCrit Care Med 2020; 201 (11) 1380-1388
    CrossrefPubMedGoogle Scholar
  • 5 Daneshvar MI, Hollis DG, Steigerwalt AG. et al. Assignment of CDC weak oxidizer group 2 (WO-2) to the genus Pandoraea and characterization of three new Pandoraea genomospecies. J ClinMicrobiol 2001; 39 (05) 1819-1826
    Google Scholar
  • 6 Elborn JS. Cystic fibrosis. Lancet 2016; 388 (10059) 2519-2531
    CrossrefPubMedGoogle Scholar
  • 7 Aravena-Román M. Cellular fatty acid-deficient Pandoraea isolated from a patient with cystic fibrosis. J Med Microbiol 2008; 57 (Pt 2) 252
    CrossrefPubMedGoogle Scholar
  • 8 Stryjewski ME, LiPuma JJ, Messier Jr RH, Reller LB, Alexander BD. Sepsis, multiple organ failure, and death due to Pandoraea pnomenusa infection after lung transplantation. J ClinMicrobiol 2003; 41 (05) 2255-2257
    Google Scholar
  • 9 Falces-Romero I, Gutiérrez-Arroyo A, Romero-Gómez MP. Catheter-associated bacteremia by Pandoraea pnomenusa in an infant with acute lymphoblastic leukemia. Med Clin (English edition) 2016; 147 (03) 1320
    Google Scholar
  • 10 Johnson LN, Han JY, Moskowitz SM, Burns JL, Qin X, Englund JA. Pandoraea bacteremia in a cystic fibrosis patient with associated systemic illness. Pediatr Infect Dis J 2004; 23 (09) 881-882
    CrossrefPubMedGoogle Scholar