CC BY-NC-ND 4.0 · The Arab Journal of Interventional Radiology 2018; 02(03): S23
DOI: 10.1055/s-0041-1730708

Below the Knee Angioplasty in Diabetic Patients: Predictors of Major Adverse Clinical Outcome

Mohamed Ali Kashkoush
National Institute of Diabetes and Endocrinology, Cairo, Egypt
Ahmed Abdelhamid Taha
Faculty of Medicine Cairo University, Cairo, Egypt
Ahmed Sayed Mostafa
Faculty of Medicine Cairo University, Cairo, Egypt
› Author Affiliations

Background: The aim of the study was to determine the predictors of clinical outcome following percutaneous transluminal angioplasty (PTA) in diabetic patients with below-knee atherosclerotic lesions causing critical limb ischemia (CLI). Methods: Over 1 year, 67 patients underwent below-knee PTA. All of these patients were CLI patients (patients either manifested by rest pain or tissue loss). The composite end point of interest was major adverse clinical outcome (MACO) of the treated limb at follow-up which was defined as clinical failure, need for subsequent endovascular, or surgical revascularization or amputation. Freedom from MACO was assessed using Kaplan–Meier curves. Results: Successful limb salvage was seen in 88% with CLI. Complete wound healing was achieved in 76% of cases with a mean time to healing of 10.7 months. Significant predictors of MACO were technical failure (P = 0.002) and occlusive lesions (P =e 0.019). We reported a percentage of 76.1% freedom of MACO. Conclusion: Below-knee PTA is a feasible therapeutic option in this diabetic population. Technical failure and occlusive lesions may be predictors of adverse outcome.

Publication History

Article published online:
11 May 2021

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