CC BY-NC-ND 4.0 · The Arab Journal of Interventional Radiology 2018; 02(03): S23
DOI: 10.1055/s-0041-1730706
Abstract

Real-Time Elastography-Guided Prostate Biopsy Improves Cancer Detection Following Transrectal Ultrasound Biopsy: A Prospective Study of 392 Patients

Chaffa Aimeur
Bab El Oued Universitary Hospital, Algiers, Algeria
,
Mohamed Abdelmadjid Habba
Bab El Oued Universitary Hospital, Algiers, Algeria
,
Mounir Tabouche
Bab El Oued Universitary Hospital, Algiers, Algeria
,
Amine Habouchi
Bab El Oued Universitary Hospital, Algiers, Algeria
,
Radia Ait Chalal
Bab El Oued Universitary Hospital, Algiers, Algeria
,
Boudjema Mansouri
Bab El Oued Universitary Hospital, Algiers, Algeria
› Author Affiliations

Background: Prostate cancer, the most common malignancy and the second leading cause of cancer-related death in men, is not only a major medical problem but also a significant public health issue because it may cause significant economic burden. Methods: Our study includes 392 men suspected of having prostate cancer on the basis of clinical and biochemical evaluation who underwent whole prostate analysis by real-time elastography (RTE) with identification of suspicious areas (hard areas) which are biopsied (2 cores by lesion) followed by 12 core systematic biopsy. We analyzed respectively the cancer detection rate of RTE and systematic biopsy. Results: Mean age of patients was 68.32 years (range 39–85) and mean prostate-specific antigen level was 12.73 (range 0.86–100). Cancer was found in 208 of 392 patients (53.06%). The rate of high-grade tumors (Gleason 8 and 9) was 19.71% (41 cases). RTE detected cancer in 71 patients (34.13%) and systematic biopsy detected it in 49 (23.55%). Positive cancer cores were found in RTE-targeted cores in 83 of 142 cases (58.45%) and in systematic cores in 511 of 4704 (10.86%). The cancer detection rate per core was 5.38-fold greater for targeted than for systematic biopsy. Comparison of B-mode US and RTE diagnostic accuracy in the detection of tumours located in the peripheral zone of the prostate gland showed a significant difference. Conclusion: RTE is an interesting complement to grayscale US to direct prostate biopsies; it reached a higher accuracy than B-mode ultrasound in the evaluation of the peripheral zone of prostate and in the selection of appropriate biopsy sites.



Publication History

Article published online:
11 May 2021

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