CC BY-NC-ND 4.0 · The Arab Journal of Interventional Radiology 2018; 02(03): S10
DOI: 10.1055/s-0041-1730673
Abstract

Combined Treatment, Transarterial Embolization, and Microwave Ablation in Patients with Hepatocellular Carcinoma

Mohamed Zaitoun
Zagazig University Hospitals, Zagazig, Egypt
› Author Affiliations

Background: This study aimed to compare the feasibility and benefit of combined therapy (transarterial embolization [TACE] + microwave ablation [MWA]) versus TACE or MWA alone in the treatment of hepatocellular carcinoma (HCC) >3 and <5 cm. Methods: During 3 years, 150 consecutive patients with HCC >3 and <5 cm were divided into three groups: Group 1: fifty HCC patients who underwent TACE, Group 2: fifty HCC patients who underwent MWA, and Group 3: fifty HCC patients who received combined therapy with TACE followed by MWA after 1 month. The mean age was 57 years, 94 (62.7%) patients were males. Follow-up with triphasic computed tomography (CT) was performed after 1 month and then every 3 months for 1 year. Results: After 1 month, complete response was detected in 27 cases (54%) in Group 1, 22 cases (44%) in Group 2, and 50 cases (100%) in Group 3; partial response in 8 cases (16%) in Group 1 and 5 cases (10%) in Group 2; and progressive disease in 15 cases (30%) in Group 1 and 23 cases (46%) in Group 2. Recurrence rate after 1 year was 38 cases (72%) in Group 1, 40 cases (80%) in Group 2, and 9 cases (18%) in Group 3. Disease-free survival rate at 12 months was 12 cases (24%) in Group 1, 10 cases (20%) in Group 2, and 41 cases (82%) in Group 3. Conclusion: Combined therapy (TACE + MWA) in HCC >3 cm and <5 cm is better than TACE or MWA alone concerning the recurrence rate and disease-free survival rate.



Publication History

Article published online:
11 May 2021

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