CC BY-NC-ND 4.0 · The Arab Journal of Interventional Radiology 2018; 02(03): S4-S5
DOI: 10.1055/s-0041-1730657
Abstract

Mechanical Thrombectomy within 6 h after Symptom Onset in Ischemic Stroke

Afra Sultan Muesem Alfalahi
Rashid Hospital, Dubai, UAE
,
Ayman Atmaz Alsibaie
Rashid Hospital, Dubai, UAE
,
Ahmad Saadat
Rashid Hospital, Dubai, UAE
,
Hamda Ahmad Kamalboor
Rashid Hospital, Dubai, UAE
› Author Affiliations

Background: Acute stroke consequence results on a heavy burden over affected society members ranging from physical disability, health-care resources, and financial support required. The aim of the study is to assess the clinical outcome postmechanical thrombectomy with or without intravenous (IV) or intraarterial tissue-plasminogen activator (t-PA) for the treatment of acute stroke. Methods: During a 3-year period at single center in Dubai, UAE, a total of 40 patients who could be treated within 6 h after the onset of symptoms of acute ischemic stroke to receive either medical therapy (including IV or intraarterial alteplase when eligible) and endovascular therapy with a stent retriever (thrombectomy group) or medical therapy alone (IV t-PA) (control group). All patients had confirmed proximal anterior circulation occlusion and the absence of a large infarct on neuroimaging. The primary outcome was the severity of clinical disability at 72 h and at the time of discharge, as measured by the National Institutes of Health Stroke Scale score and modified Rankin scale. Results: Thrombectomy reduced the severity of disability over the range of the National Institutes of Health Stroke Scale score and modified Rankin scale. Conclusion: Among patients with anterior circulation stroke who could be treated within 6 h after symptom onset, stent retriever thrombectomy reduced the severity of poststroke disability and increased the rate of functional independence.



Publication History

Article published online:
11 May 2021

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