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DOI: 10.1055/s-0041-1730372
Vein of Galen Aneurysmal Malformations in Pediatric Patients Submitted to Endovascular Treatment: Report of 3 Cases
Malformações aneurismáticas da veia de Galeno em pacientes pediátricos submetidos a tratamento endovascular: Relato de 3 casos
Abstract
Objective To report three cases of vein of Galen aneurysmal malformation (VGAM) in pediatric patients treated at the hemodynamics lab of Hospital Santa Isabel (HSI) in Blumenau, state of Santa Catarina, Brazil, from 2006 to 2020. Clinical presentation, endovascular treatment, and postprocedure evolution to date are included.
Case description Three children aged 5 to 12 months with cardiac, respiratory, or neurological damage in the neonatal stage, were referred to the neurosurgery service and diagnosed with VGAM. The three patients underwent endovascular embolization of the malformation, with different clinical evolution throughout outpatient follow-up.
Conclusion Vein of Galen aneurysmal malformations are uncommon vascular abnormalities that, until the advent of endovascular embolization, were associated with high morbidity and mortality rates. Its prognosis is linked with initial clinic, early diagnosis, and timely surgical correction.
Resumo
Objetivo Relatar três casos de malformação aneurismática da veia de Galeno (MAVG) em faixa etária pediátrica atendidos no setor de hemodinâmica do Hospital Santa Isabel (HSI) de Blumenau, SC no período de 2006 a 2020, relatando a apresentação clínica, o tratamento endovascular bem como a evolução pós-procedimento até o presente ano.
Descrição do caso Os relatos descrevem 3 crianças entre 5 e 12 meses de idade que apresentaram alterações cardíacas, respiratórias ou neurológicas no período neonatal, encaminhadas para o serviço de neurocirurgia e diagnosticadas com MAVG. Os três casos foram submetidos à embolização endovascular da malformação, diferindo na evolução clínica ao longo do seguimento ambulatorial.
Conclusão As MAVGs são anomalias vasculares incomuns de elevada taxa de morbimortalidade até o advento da embolização endovascular. O seu prognóstico está ligado à clínica inicial, ao precoce diagnóstico e à correção cirúrgica no momento adequado.
Keywords
arteriovenous malformations - intracranial aneurysm - vein of Galen - endovascular procedures - pediatrics - neurosurgeryPalavras-chave
malformações arteriovenosas - aneurisma intracraniano - veia de Galeno - procedimentos endovasculares - pediatria - neurocirurgiaThis study took place at FURB and Santa Isabel Hospital at Blumenau, Santa Catarina- Brazil.
Publication History
Received: 16 August 2020
Accepted: 22 February 2021
Article published online:
11 August 2021
© 2021. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Sivasankar R, Limaye US, Wuppalapati S, Shrivastava M. Endovascular Management of Vein of Galen Aneurysmal Malformations: A Retrospective Analysis over a 15-Year Period. J Vasc Interv Neurol 2019; 10 (03) 23-29
- 2 daSilva JFC, Lacerda DAM, Machado GHS, Nihi MA, João PRD. Malformação Arteriovenosa da Veia de Galeno no Recém- Nascido. Relato de Caso e Revisão de Literatura. Jornal Brasileiro de Neurocirurgia. 2017; 27 (03) 231-239 Brazilian.
- 3 Mortazavi MM, Griessenauer CJ, Foreman P. et al. Vein of Galen aneurysmal malformations: critical analysis of the literature with proposal of a new classification system. J Neurosurg Pediatr 2013; 12 (03) 293-306
- 4 Berenstein A, Paramasivam S, Sorscher M, Molofsky W, Meila D, Ghatan S. Vein of Galen Aneurysmal Malformation: Advances in Management and Endovascular treatment. Neurosurgery 2019; 84 (02) 469-478
- 5 Siqueira MG. Tratado de Neurocirurgia. Brasil: Manole; 2015
- 6 Taffin H, Maurey H, Ozanne A. et al. Long-term outcome of vein of Galen malformation. Dev Med Child Neurol 2019; 1-6
- 7 Yan J, Wen J, Gopaul R, Zhang CY, Xiao SW. Outcome and complications of endovascular embolization for vein of Galen malformations: a systematic review and meta-analysis. J Neurosurg 2015; 123 (04) 872-890
- 8 Spazzapan P, Milosevic Z, Velnar T. Vein of Galen aneurismal malformations - clinical characteristics, treatment and presentation: Three cases report. World J Clin Cases 2019; 7 (07) 855-862
- 9 Lasjaunias PL, Chng SM, Sachet M, Alvarez H, Rodesch G, Garcia-Monaco R. The management of vein of Galen aneurysmal malformations. Neurosurgery 2006; 59 (05, Suppl 3): discussion S3–S13 S184-S194
- 10 Lasjaunias P. Vascular diseases in neonates, infants and children. New York: Springer-Verlag; 1997
- 11 Seleznev P, Orlov K, Berestov V. et al. Outcomes of endovascular treatment of vein of galen aneurysmal malformation in neonates. J Neurointerv Surg 2020; 12: A20-A21
- 12 Bhatia K, Mendes Pereira V, Krings T. et al. Factors contributing to major neurological complication from Vein of Galen malformation embolization. JAMA Neurol 2020; 77 (08) 992-999