CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2021; 31(01): 091-101
DOI: 10.1055/s-0041-1729673
Original Article

Role of Diffusion-Weighted Imaging in the Evaluation of Perianal Fistulae

Deb K. Boruah
1  Department of Radio-Diagnosis, Tezpur Medical College and Hospital, Tezpur, Assam, India
,
Karuna Hazarika
1  Department of Radio-Diagnosis, Tezpur Medical College and Hospital, Tezpur, Assam, India
,
Halimuddin Ahmed
1  Department of Radio-Diagnosis, Tezpur Medical College and Hospital, Tezpur, Assam, India
,
Krishna K. Borah
1  Department of Radio-Diagnosis, Tezpur Medical College and Hospital, Tezpur, Assam, India
,
Samudra Borah
1  Department of Radio-Diagnosis, Tezpur Medical College and Hospital, Tezpur, Assam, India
,
Seema Malakar
1  Department of Radio-Diagnosis, Tezpur Medical College and Hospital, Tezpur, Assam, India
,
Nobojit Hajoari
1  Department of Radio-Diagnosis, Tezpur Medical College and Hospital, Tezpur, Assam, India
› Author Affiliations

Abstract

Background Magnetic resonance imaging (MRI) is the imaging modality of choice for evaluating perianal fistulae, due to its ability to show the relationship of perianal fistulae with anal sphincters, fistula extensions, secondary ramifications and associated complications.

Aim To evaluate the role of diffusion-weighted MRI in the evaluation of perianal fistulae.

Settings and Design A hospital-based cross-sectional study.

Materials and Methods The study group composed of 47 patients of perianal fistula. MRI with diffusion-weighted imaging (DWI) was performed with Philips 0.5 T Ingenia scanner. DWI with different b-values (b = 50, b = 400, and b = 800 smm2) were obtained. The MRI findings were correlated with local clinical examination and or surgical findings.

Statistical Analysis Used Chi-square test, independent samples t-test, and receiver operating characteristic curve analysis.

Result Fifty-nine perianal fistulas in 47 patients were included in the study sample. The visibility of perianal fistula on DWI was less than T2-weighted (T2W) and combined DWI-T2W images. Distinctly visualized (visibility score 2) perianal fistulas were observed in 47 fistulas (79.6%) on DWI, 54 (91.5%) on T2W, and 58 (98.3%) on DWI-T2W images. The mean of apparent diffusion coefficient (ADC) values of active fistula was 0.972 ± 0.127 [SD] 10−3 mm2/s and inactive was 1.232 ± 0.185 [SD] 10−3 mm2/s with a significant difference (p-value < 0.0005). A cut-off mean ADC value of 1.105 × 10−3 mm2/s was used to differentiate active from the inactive fistula with a sensitivity of 87.5% and specificity of 73.3%.

Conclusion Combined DWI-T2W evaluation had a better performance in the detection of fistula than DWI or T2W alone. DWI with mean ADC calculation had a good performance in differentiating active from the inactive fistulas.



Publication History

Publication Date:
23 May 2021 (online)

© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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