CC BY-NC-ND 4.0 · Journal of Clinical Interventional Radiology ISVIR 2021; 05(03): 142-149
DOI: 10.1055/s-0041-1728983
Original Article

Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae

Nishtha Yadav
1   Department of Radiology, Super Speciality Hospital, NSCB Medical College, Jabalpur, Madhya Pradesh, India
,
Shivanand Gamanagatti
2   Department of Radiology, All India Institute of Medical Sciences, New Delhi, India
,
Raju Sharma
2   Department of Radiology, All India Institute of Medical Sciences, New Delhi, India
,
Sanjay Kumar Aggarwal
3   Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India
,
V. K. Bansal
4   Department of Surgery, All India Institute of Medical Sciences, New Delhi, India
,
Devasenathipathy Kandasamy
2   Department of Radiology, All India Institute of Medical Sciences, New Delhi, India
,
V. Seenu
4   Department of Surgery, All India Institute of Medical Sciences, New Delhi, India
› Institutsangaben

Abstract

Introduction Arteriovenous fistulae (AVF) for hemodialysis (HD) are prone to development of multiple complications, which can lead to nonfunctioning of the fistula. We report outcomes of endovascular management for dysfunctional HD AVF.

Materials and Methods In this prospective study, patients (43 men, 28 women, mean age 47.4 years) with clinical signs and symptoms of dysfunctional HD AVF and referred to interventional radiology for endovascular management were included. The most common clinical presentation included low flows during hemodialysis (n = 20), absent flow (n = 37), and failure of fistula maturation (n = 14). Patients with central venous obstruction who presented with limb swelling were excluded from this study. Patients underwent venography, venoplasty and thrombectomy, as appropriate, to salvage the fistula. The study outcomes were technical success, hemodynamic success, and clinical success of endovascular therapies in salvaging the fistulae.

Results The technical, hemodynamic and clinical success rates of endovascular therapy for low-flow symptoms were 95%, 70% and 95%, respectively. Among patients who presented with absent flow, endovascular therapy had 81% technical success, 78.3% hemodynamic success, and 81% clinical success. Endovascular therapy was associated with 64.2% technical success, 57.1% hemodynamic success, and 64.2% clinical success in patients presenting with failed maturation of the fistula. The overall clinical success rate was 58/71 (81.7%) and failure rate was 13/71 (18.3%). The overall complication rate of endovascular therapy was 8.4% and the complications included vein rupture in 5 (7%) and balloon rupture in 1 (1.4%).

Conclusion Endovascular therapy for salvage of nonfunctioning hemodialysis AVF is associated with a high-clinical success rate (81.7%) and low-complication rate.



Publikationsverlauf

Artikel online veröffentlicht:
01. Juni 2021

© 2021. Indian Society of Vascular and Interventional Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Schieppati A, Remuzzi G. Chronic renal diseases as a public health problem: epidemiology, social, and economic implications. Kidney Int Suppl 2005; 68 (98) S7-S10
  • 2 Jha V. Current status of end-stage renal disease care in India and Pakistan. Kidney Int Suppl 2013; 3 (02) 157-160
  • 3 Santoro D, Benedetto F, Mondello P. et al Vascular access for hemodialysis: current perspectives. Int J Nephrol Renov Dis 2014; 7: 281-294
  • 4 Le L, Brooks A, Donovan M. Smith TA, Sternbergh WC III, Bazan HA. Transradial approach for percutaneous intervention of malfunctioning arteriovenous accesses. J Vasc Surg 2015; 61 (03) 747-753
  • 5 Bittl JA. Catheter interventions for hemodialysis fistulas and grafts. JACC Cardiovasc Interv 2010; 3 (01) 1-11
  • 6 Nikam MD, Ritchie J, Jayanti A, Bernstein OA, Ebah L, Brenchley P, Hutchison A, Chalmers N, Mitra S. Acute Arteriovenous Access Failure: Long-term outcomes of endovascular salvage and assessment of co-variates affecting patency. Nephron 2015; 129: 241-246
  • 7 Cohen A, Korzets A, Neyman H. et al Endovascular interventions of juxtaanastomotic stenoses and thromboses of hemodialysis arteriovenous fistulas. J Vasc Interv Radiol 2009; 20 (01) 66-70
  • 8 Yildiz I. The efficacy of paclitaxel drug-eluting balloon angioplasty versus standard balloon angioplasty in stenosis of native hemodialysis arteriovenous fistulas: an analysis of clinical success, primary patency and risk factors for recurrent dysfunction. Cardiovasc Intervent Radiol 2019; 42 (05) 685-692
  • 9 Miller G, Friedman A. Balloon-assisted maturation of arteriovenous fistulas. Endovasc Today 2010; 46-54
  • 10 Turmel-Rodrigues L, Mouton A, Birmelé B. et al Salvage of immature forearm fistulas for haemodialysis by interventional radiology. Nephrol Dial Transplant 2001; 16 (12) 2365-2371
  • 11 Beathard GA, Settle SM, Shields MW. Salvage of the nonfunctioning arteriovenous fistula. Am J Kidney Dis 1999; 33 (05) 910-916
  • 12 Miller GA, Hwang W, Preddie D, Khariton A, Savransky Y. Percutaneous salvage of thrombosed immature arteriovenous fistulas. Semin Dial 2011; 24 (01) 107-114
  • 13 Nassar GM, Nguyen B, Rhee E, Achkar K. Endovascular treatment of the “failing to mature” arteriovenous fistula. Clin J Am Soc Nephrol 2006; 1 (02) 275-280
  • 14 Park HS, Lee YH, Kim HW. et al Usefulness of assisted procedures for arteriovenous fistula maturation without compromising access patency. Hemodial Int 2017; 21 (03) 335-342
  • 15 Lee SJ, Jeon GS, Lee B, Lee G, Lee JJ. Endovascular management in immature arteriovenous fistula for hemodialysis. Medicine (Baltimore) 2018; 97 (36) e12211
  • 16 Bittl JA, Feldman RL. Cutting balloon angioplasty for undilatable venous stenoses causing dialysis graft failure. Catheter Cardiovasc Interv 2003; 58 (04) 524-526
  • 17 Vesely TM. Percutaneous transluminal angioplasty for the treatment of failing hemodialysis grafts and fistulae. Semin Dial 1998; 11 (06) 351-359
  • 18 Bittl JA. Venous rupture during percutaneous treatment of hemodialysis fistulas and grafts. Catheter Cardiovasc Interv 2009; 74 (07) 1097-1101
  • 19 Rundback JH, Leonardo RF, Poplausky MR, Rozenblit G. Venous rupture complicating hemodialysis access angioplasty: percutaneous treatment and outcomes in seven patients. Am J Roentgenol 1998; 171 (04) 1081-1084