CC BY-NC-ND 4.0 · J Neurosci Rural Pract 2021; 12(03): 478-482
DOI: 10.1055/s-0041-1727558
Original Article

Study of Short Latency Somatosensory and Brain Stem Auditory Evoked Potentials Patients with Acute Ischemic Stroke Involving Middle Cerebral Artery Territory

Abhishek Miryala
1  Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India
,
1  Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India
,
Anish Mehta
1  Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India
,
R. Pradeep
1  Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India
,
Purushottam Acharya
1  Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India
,
Rangasetty Srinivasa
1  Department of Neurology, MS Ramaiah Medical College & Hospital, Bengaluru, Karnataka, India
› Author Affiliations
Funding None.

Abstract

Background The precise timings of evoked potentials in evaluating the functional outcome of stroke have remained indistinct. Few studies in the Indian context have studied the outcome of early prognosis of stroke utilizing evoked potentials.

Objective The aim of this study was to determine somatosensory evoked potentials (SSEPs) and brain stem auditory evoked potentials (BAEPs), their timing and abnormalities in acute ischemic stroke involving the middle cerebral artery (MCA) territory and to correlate SSEP and BAEP with the functional outcome (National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale (mRS) and Barthel’s index) at 3 months.

Methods MCA territory involved acute ischemic stroke patients (n = 30) presenting consecutively to the hospital within 3 days of symptoms onset were included. Details about clinical symptoms, neurological examination, treatment, NIHSS score, mRS scores were collected at the time of admission. All patients underwent imaging of the brain and were subjected to SSEP and BAEP on two occasions, first at 1 to 3 days and second at 4 to 7 days from the onset of stroke. At 3 months of follow-up, NIHSS, mRS, and Barthel’s index were recorded.

Results P37 and N20 amplitude had a strong negative correlation (at 1–3 and 4–7 days) with NIHSS at admission, NIHSS at 3 months, mRS at admission, and mRS at 3 months and a significant positive correlation with Barthel’s index (p < 0.0001). BAEP wave V had a negative correlation (at 1–3 and 4–7 days) with NIHSS at admission, NIHSS at 3 months, mRS at admission, and mRS at 3 months and a positive correlation with Barthel’s index (p < 0.0001).

Conclusion SSEP abnormalities recorded on days 4 to 7 from onset of stroke are more significant than those recorded within 1 to 3 days of onset of stroke; hence, the timing of 4 to 7 days after stroke onset can be considered as better for predicting functional outcome.



Publication History

Publication Date:
10 May 2021 (online)

© 2021. Association for Helping Neurosurgical Sick People. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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