Semin Neurol 2021; 41(03): 291-302
DOI: 10.1055/s-0041-1725948
Review Article

Myelopathies from Neoplasms

1  Division of Neurology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Jorg Dietrich
2  Division of Neuro-Oncology, Department of Neurology, Massachusetts General Hospital Cancer Center, Boston, MA
› Author Affiliations


Benign and malignant tumors can be an important cause of myelopathy. Patients may present with a wide range of neurologic symptoms including back and neck pain, weakness, sensory abnormalities, and bowel and bladder dysfunction. Management can be challenging depending on the location and underlying biology of the tumor. Neuroimaging of the spine is an important component of diagnostic evaluation and patient management both during initial evaluation and when monitoring after treatment. This article provides a systematic and practical review of neoplasms that can cause myelopathy. Unique imaging and biological features of distinct tumors are discussed, and their management strategies are reviewed.

Publication History

Publication Date:
24 May 2021 (online)

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