Int J Angiol
DOI: 10.1055/s-0041-1725183
Case Report

COVID-19 in an Asymptomatic Renal Transplant Recipient Employed in the Health Care Setting: A Case Report

Harsha Adnani
1  The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York
,
Akshay Khatri
2  Division of Infectious Diseases, Department of Medicine, Northwell Health, Manhasset, New York
,
Nirav Agrawal
1  The Feinstein Institute for Medical Research, Northwell Health, Manhasset, New York
,
Ernesto Molmenti
3  Department of Surgery, North Shore University Hospital, Northwell Health, Manhasset, New York
,
Madhu Bhaskaran
4  Division of Nephrology and Transplant Nephrology, Department of Medicine, Northwell Health, Manhasset, New York
› Author Affiliations

Abstract

During the ongoing pandemic, there have been varying presentations of coronavirus disease 2019 (COVID-19) infection, with the concern that patients who are immunosuppressed (due to underlying medical conditions and/or therapies) are at higher risk of severe disease. We report the case of an elderly renal transplant recipient working in a long-term health care facility who was being monitored by weekly surveillance testing and tested positive for COVID-19 by polymerase chain reaction (PCR) testing, despite having no clinical symptoms. He recovered with supportive care, despite being on multiple long-term immunosuppressant drugs and having multiple comorbidities. Additionally, it was found that he did not mount an antibody response, when he tested negative by serologic testing. Through this case, we wish to highlight the unique clinical scenario of asymptomatic patients who may have an underwhelming immune response to COVID-19, but may nevertheless be an important source of dissemination. We further discuss the probable mechanism of such asymptomatic presentations in immunosuppressed patients, while reinforcing the importance of self-isolation of COVID-19 patients (particularly in asymptomatic health care workers).



Publication History

Received: 13 October 2020

Accepted: 19 January 2021

Publication Date:
11 March 2021 (online)

© 2021. International College of Angiology. This article is published by Thieme.

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