Endoscopy 2021; 53(S 01): S129
DOI: 10.1055/s-0041-1724599
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Prolonged Gastric Transit Time in Small-Bowel Capsule Endoscopy - Which Patients are at Risk and What Implications?

M Freitas
1   Hospital da Senhora da Oliveira, Gastroenterology Department, Guimarães, Portugal
2   School of Medicine, University of Minho, Life and Health Sciences Research Institute (ICVS), Braga, Portugal
3   PT Government Associate Laboratory, ICVS/3B’s, Braga/Guimarães, Portugal
,
V Macedo Silva
1   Hospital da Senhora da Oliveira, Gastroenterology Department, Guimarães, Portugal
2   School of Medicine, University of Minho, Life and Health Sciences Research Institute (ICVS), Braga, Portugal
3   PT Government Associate Laboratory, ICVS/3B’s, Braga/Guimarães, Portugal
,
P Boal Carvalho
1   Hospital da Senhora da Oliveira, Gastroenterology Department, Guimarães, Portugal
2   School of Medicine, University of Minho, Life and Health Sciences Research Institute (ICVS), Braga, Portugal
3   PT Government Associate Laboratory, ICVS/3B’s, Braga/Guimarães, Portugal
,
B Rosa
1   Hospital da Senhora da Oliveira, Gastroenterology Department, Guimarães, Portugal
2   School of Medicine, University of Minho, Life and Health Sciences Research Institute (ICVS), Braga, Portugal
3   PT Government Associate Laboratory, ICVS/3B’s, Braga/Guimarães, Portugal
,
MJ Moreira
1   Hospital da Senhora da Oliveira, Gastroenterology Department, Guimarães, Portugal
2   School of Medicine, University of Minho, Life and Health Sciences Research Institute (ICVS), Braga, Portugal
3   PT Government Associate Laboratory, ICVS/3B’s, Braga/Guimarães, Portugal
,
J Cotter
1   Hospital da Senhora da Oliveira, Gastroenterology Department, Guimarães, Portugal
2   School of Medicine, University of Minho, Life and Health Sciences Research Institute (ICVS), Braga, Portugal
3   PT Government Associate Laboratory, ICVS/3B’s, Braga/Guimarães, Portugal
› Author Affiliations
 

Aims Prolonged gastric transit time (PGTT) is a commonly described cause for incomplete capsule endoscopy examination. We aimed to evaluate the prevalence and identify risk factors for PGTT, and to assess its impact on the rate of incomplete examinations.

Methods Retrospective study including consecutive patients undergoing small-bowel capsule endoscopy (SBCE) between January 2014 and August 2020. Patients with PGTT were consecutively included. Patients without PGTT were randomized (controls) in a 1:1 ratio. PGTT was defined as SBCE remaining in the stomach for more than 1h due to delayed gastric transit, as checked with the routine use of the Real Time Viewer, requiring an intervention such as prokinetic administration and/or endoscopically assisted capsule delivery into the duodenum.

Results PGTT occurred in 45/957 patients (4.7 %). Both groups were similar regarding indication and inpatient status (p≥0.05). The mean gastric transit was higher in PGTT group (2h34±40min vs 39±41min; p < 0.001), but the mean small bowel transit was similar between groups (4h48±2h11min vs 4h38±1h36min; p = 0.70). PGTT group did not have a significant higher rate of incomplete exams (9.3 % vs 4.7 %; p = 0.68). Patients with PGTT presented more frequently with inadequate small-bowel preparation (p = 0.01). Older age (mean age of 52±20 vs 44±18 years; p = 0.045), female sex (44.2 % vs 18.6 %; p = 0.01), diabetes (25.6 % vs 9.3 %; p = 0.047) and psychotropic medication use (30.2 % vs 11.6 %; p = 0.03) were risk factors for PGTT.

Conclusions PGTT was a relatively common event, associated with higher rate of inadequate small-bowel preparation. Older age, female sex, diabetes and psychotropic medication use were risk factors for PGTT. However, it was not associated with a higher rate of incomplete exams in our cohort, likely because we routinely perform real time monitoring of the capsule passage and early preventive interventions such as prokinetic administration and/or endoscopically assisted capsule delivery to optimize the SBCE examination time.

Citation: Freitas M, Macedo Silva V, Boal Carvalho P et al. eP100 PROLONGED GASTRIC TRANSIT TIME IN SMALL-BOWEL CAPSULE ENDOSCOPY - WHICH PATIENTS ARE AT RISK AND WHAT IMPLICATIONS? Endoscopy 2021; 53: S129.



Publication History

Article published online:
19 March 2021

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