Int J Angiol 2021; 30(01): 029-039
DOI: 10.1055/s-0041-1724019
Review Article

Optical Coherence Tomography of the Coronary Arteries

Robert Roland
1   Department of Cardiology, Motol University Hospital, Charles University, Prague, Czech Republic
,
Josef Veselka
1   Department of Cardiology, Motol University Hospital, Charles University, Prague, Czech Republic
› Author Affiliations
Funding None.

Abstract

Intravascular imaging, particularly optical coherence tomography, has brought significant improvement in diagnostic and therapeutical approaches to coronary artery disease and has offered superior high-resolution visualization of coronary arteries. The ability to obtain images of intramural and transmural coronary structures allows the study of the process of atherosclerosis, effect of therapies, mechanism of acute coronary syndrome and stent failure, and performance of new devices and enables the interventional cardiologist to optimize the effect of percutaneous coronary intervention. In this review, we provide the summary of the latest published data on clinical use of optical coherence tomography as well as practical algorithm for optical coherence tomography-guided percutaneous coronary intervention for daily interventional practice.

Disclosure

Both authors have nothing to disclose.




Publication History

Article published online:
12 February 2021

© 2021. International College of Angiology. This article is published by Thieme.

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  • References

  • 1 Topol EJ, Nissen SE. Our preoccupation with coronary luminology. The dissociation between clinical and angiographic findings in ischemic heart disease. Circulation 1995; 92 (08) 2333-2342
  • 2 Fedele S, Biondi-Zoccai G, Kwiatkowski P. et al. Reproducibility of coronary optical coherence tomography for lumen and length measurements in humans (The CLI-VAR [Centro per la Lotta contro l'Infarto-VARiability] study). Am J Cardiol 2012; 110 (08) 1106-1112
  • 3 Kubo T, Akasaka T, Shite J. et al. OCT compared with IVUS in a coronary lesion assessment: the OPUS-CLASS study. JACC Cardiovasc Imaging 2013; 6 (10) 1095-1104
  • 4 Prati F, Di Vito L, Biondi-Zoccai G. et al. Angiography alone versus angiography plus optical coherence tomography to guide decision-making during percutaneous coronary intervention: the Centro per la Lotta contro l'Infarto-Optimisation of Percutaneous Coronary Intervention (CLI-OPCI) study. EuroIntervention 2012; 8 (07) 823-829
  • 5 Prati F, Romagnoli E, Burzotta F. et al. Clinical impact of OCT findings during PCI: the CLI-OPCI II study. JACC Cardiovasc Imaging 2015; 8 (11) 1297-1305
  • 6 Iannaccone M, D'Ascenzo F, Frangieh AH. et al. Impact of an optical coherence tomography guided approach in acute coronary syndromes: a propensity matched analysis from the international FORMIDABLE-CARDIOGROUP IV and USZ registry. Catheter Cardiovasc Interv 2017; 90 (02) E46-E52
  • 7 Sheth TN, Kajander OA, Lavi S. et al. Optical coherence tomography-guided percutaneous coronary intervention in ST-segment-elevation myocardial infarction: a prospective propensity-matched cohort of the thrombectomy versus percutaneous coronary intervention alone trial. Circ Cardiovasc Interv 2016; 9 (04) e003414
  • 8 Wijns W, Shite J, Jones MR. et al. Optical coherence tomography imaging during percutaneous coronary intervention impacts physician decision-making: ILUMIEN I study. Eur Heart J 2015; 36 (47) 3346-3355
  • 9 Maehara A, Ben-Yehuda O, Ali Z. et al. Comparison of stent expansion guided by optical coherence tomography versus intravascular ultrasound: the ILUMIEN II study (observational study of optical coherence tomography [OCT] in patients undergoing fractional flow reserve [FFR] and percutaneous coronary intervention). JACC Cardiovasc Interv 2015; 8 (13) 1704-1714
  • 10 Ali ZA, Maehara A, Généreux P. et al; ILUMIEN III: OPTIMIZE PCI Investigators. Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial. Lancet 2016; 388 (10060): 2618-2628
  • 11 Kubo T, Shinke T, Okamura T. et al; OPINION Investigators. OPtical frequency domain imaging vs. INtravascular ultrasound in percutaneous coronary InterventiON (OPINION trial): one-year angiographic and clinical results. Eur Heart J 2017; 38 (42) 3139-3147
  • 12 Jones DA, Rathod KS, Koganti S. et al. Angiography alone versus angiography plus optical coherence tomography to guide percutaneous coronary intervention: outcomes from the Pan-London PCI cohort. JACC Cardiovasc Interv 2018; 11 (14) 1313-1321
  • 13 Meneveau N, Souteyrand G, Motreff P. et al. Optical coherence tomography to optimize results of percutaneous coronary intervention in patients with non-ST-elevation acute coronary syndrome: results of the multicenter, randomized DOCTORS study (Does Optical Coherence Tomography Optimize Results of Stenting). Circulation 2016; 134 (13) 906-917
  • 14 Antonsen L, Thayssen P, Maehara A. et al. Optical coherence tomography guided percutaneous coronary intervention with Nobori stent implantation in patients with non-ST-segment-elevation myocardial infarction (OCTACS) trial: difference in strut coverage and dynamic malapposition patterns at 6 months. Circ Cardiovasc Interv 2015; 8 (08) e002446
  • 15 Lee SY, Kim JS, Yoon HJ. et al. Early strut coverage in patients receiving drug-eluting stents and its implications for dual antiplatelet therapy: a randomized trial. JACC Cardiovasc Imaging 2018; 11 (12) 1810-1819
  • 16 Xhepa E, Bresha J, Joner M. et al. Clinical outcomes by optical characteristics of neointima and treatment modality in patients with coronary in-stent restenosis. EuroIntervention 2020. Doi: EIJ-D-20-00662
  • 17 Levine GN, Bates ER, Bittl JA. et al. 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention, 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery, 2012 ACC/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease, 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction, 2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes, and 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery. Circulation 2016; 134 (10) e123-e155
  • 18 Levine GN, Bates ER, Blankenship JC. et al; Endorsed by the Latin American Society of Interventional Cardiology, PCI WRITING COMMITTEE, STEMI WRITING COMMITTEE, ACC/AHA TASK FORCE MEMBERS. 2015 ACC/AHA/SCAI focused update on primary percutaneous coronary intervention for patients with ST-elevation myocardial infarction: an update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. Catheter Cardiovasc Interv 2016; 87 (06) 1001-1019
  • 19 Neumann FJ, Sousa-Uva M, Ahlsson A. et al; ESC Scientific Document Group. 2018 ESC/EACTS guidelines on myocardial revascularization. Eur Heart J 2019; 40 (02) 87-165
  • 20 Ibanez B, James S, Agewall S. et al; ESC Scientific Document Group. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 2018; 39 (02) 119-177
  • 21 Collet JP, Thiele H, Barbato E. et al. ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 2020
  • 22 Adlam D, Alfonso F, Maas A, Vrints C. Writing Committee. European Society of Cardiology, acute cardiovascular care association, SCAD study group: a position paper on spontaneous coronary artery dissection. Eur Heart J 2018; 39 (36) 3353-3368
  • 23 Jang IK, Bouma BE, Kang DH. et al. Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound. J Am Coll Cardiol 2002; 39 (04) 604-609
  • 24 Yabushita H, Bouma BE, Houser SL. et al. Characterization of human atherosclerosis by optical coherence tomography. Circulation 2002; 106 (13) 1640-1645
  • 25 Kubo T, Imanishi T, Takarada S. et al. Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy. J Am Coll Cardiol 2007; 50 (10) 933-939
  • 26 Nef H, Elsasser A. OCT Compendium. 1st ed.. Giessen, Germany: Universitätsklinikum Gießen und Marburg GmbH; 2016: 30
  • 27 Tearney GJ, Regar E, Akasaka T. et al; International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT). Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation. J Am Coll Cardiol 2012; 59 (12) 1058-1072
  • 28 Fujii K, Hao H, Shibuya M. et al. Accuracy of OCT, grayscale IVUS, and their combination for the diagnosis of coronary TCFA: an ex vivo validation study. JACC Cardiovasc Imaging 2015; 8 (04) 451-460
  • 29 Tanaka A, Imanishi T, Kitabata H. et al. Lipid-rich plaque and myocardial perfusion after successful stenting in patients with non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study. Eur Heart J 2009; 30 (11) 1348-1355
  • 30 Kini AS, Motoyama S, Vengrenyuk Y. et al. Multimodality intravascular imaging to predict periprocedural myocardial infarction during percutaneous coronary intervention. JACC Cardiovasc Interv 2015; 8 (07) 937-945
  • 31 Stone GW, Maehara A, Muller JE. et al; CANARY Investigators. Plaque characterization to inform the prediction and prevention of periprocedural myocardial infarction during percutaneous coronary intervention: the CANARY trial (Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow). JACC Cardiovasc Interv 2015; 8 (07) 927-936
  • 32 Kang SJ, Cho YR, Park GM. et al. Intravascular ultrasound predictors for edge restenosis after newer generation drug-eluting stent implantation. Am J Cardiol 2013; 111 (10) 1408-1414
  • 33 Kobayashi N, Mintz GS, Witzenbichler B. et al. Prevalence, features, and prognostic importance of edge dissection after drug-eluting stent implantation: an ADAPT-DES intravascular ultrasound substudy. Circ Cardiovasc Interv 2016; 9 (07) e003553
  • 34 Calvert PA, Brown AJ, Hoole SP, Obaid DR, West NE, Bennett MR. Geographical miss is associated with vulnerable plaque and increased major adverse cardiovascular events in patients with myocardial infarction. Catheter Cardiovasc Interv 2016; 88 (03) 340-347
  • 35 Wang X, Matsumura M, Mintz GS. et al. In vivo calcium detection by comparing optical coherence tomography, intravascular ultrasound, and angiography. JACC Cardiovasc Imaging 2017; 10 (08) 869-879
  • 36 Kobayashi Y, Okura H, Kume T. et al. Impact of target lesion coronary calcification on stent expansion. Circ J 2014; 78 (09) 2209-2214
  • 37 Maejima N, Hibi K, Saka K. et al. Relationship between thickness of calcium on optical coherence tomography and crack formation after balloon dilatation in calcified plaque requiring rotational atherectomy. Circ J 2016; 80 (06) 1413-1419
  • 38 Fujino A, Mintz GS, Matsumura M. et al. A new optical coherence tomography-based calcium scoring system to predict stent underexpansion. EuroIntervention 2018; 13 (18) e2182-e2189
  • 39 Kubo T, Shimamura K, Ino Y. et al. Superficial calcium fracture after PCI as assessed by OCT. JACC Cardiovasc Imaging 2015; 8 (10) 1228-1229
  • 40 Généreux P, Madhavan MV, Mintz GS. et al. Ischemic outcomes after coronary intervention of calcified vessels in acute coronary syndromes. Pooled analysis from the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) and ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trials. J Am Coll Cardiol 2014; 63 (18) 1845-1854
  • 41 Morino Y, Honda Y, Okura H. et al. An optimal diagnostic threshold for minimal stent area to predict target lesion revascularization following stent implantation in native coronary lesions. Am J Cardiol 2001; 88 (03) 301-303
  • 42 Fujii K, Carlier SG, Mintz GS. et al. Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation: an intravascular ultrasound study. J Am Coll Cardiol 2005; 45 (07) 995-998
  • 43 Hong MK, Mintz GS, Lee CW. et al. Intravascular ultrasound predictors of angiographic restenosis after sirolimus-eluting stent implantation. Eur Heart J 2006; 27 (11) 1305-1310
  • 44 Doi H, Maehara A, Mintz GS. et al. Impact of post-intervention minimal stent area on 9-month follow-up patency of paclitaxel-eluting stents: an integrated intravascular ultrasound analysis from the TAXUS IV, V, and VI and TAXUS ATLAS Workhorse, Long Lesion, and Direct Stent Trials. JACC Cardiovasc Interv 2009; 2 (12) 1269-1275
  • 45 Räber L, Mintz GS, Koskinas KC. et al; ESC Scientific Document Group. Clinical use of intracoronary imaging. Part 1: guidance and optimization of coronary interventions. An expert consensus document of the European Association of Percutaneous Cardiovascular Interventions. Eur Heart J 2018; 39 (35) 3281-3300
  • 46 Guo N, Maehara A, Mintz GS. et al. Incidence, mechanisms, predictors, and clinical impact of acute and late stent malapposition after primary intervention in patients with acute myocardial infarction: an intravascular ultrasound substudy of the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial. Circulation 2010; 122 (11) 1077-1084
  • 47 Steinberg DH, Mintz GS, Mandinov L. et al. Long-term impact of routinely detected early and late incomplete stent apposition: an integrated intravascular ultrasound analysis of the TAXUS IV, V, and VI and TAXUS ATLAS workhorse, long lesion, and direct stent studies. JACC Cardiovasc Interv 2010; 3 (05) 486-494
  • 48 Romagnoli E, Gatto L, La Manna A. et al. Role of residual acute stent malapposition in percutaneous coronary interventions. Catheter Cardiovasc Interv 2017; 90 (04) 566-575
  • 49 Souteyrand G, Amabile N, Mangin L. et al; PESTO Investigators. Mechanisms of stent thrombosis analysed by optical coherence tomography: insights from the national PESTO French registry. Eur Heart J 2016; 37 (15) 1208-1216
  • 50 Adriaenssens T, Joner M, Godschalk TC. et al; Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Investigators. Optical coherence tomography findings in patients with coronary stent thrombosis: a report of the PRESTIGE Consortium (Prevention of Late Stent Thrombosis by an Interdisciplinary Global European Effort). Circulation 2017; 136 (11) 1007-1021
  • 51 Shimamura K, Kubo T, Akasaka T. et al. Outcomes of everolimus-eluting stent incomplete stent apposition: a serial optical coherence tomography analysis. Eur Heart J Cardiovasc Imaging 2015; 16 (01) 23-28
  • 52 Sotomi Y, Onuma Y, Dijkstra J. et al. Fate of post-procedural malapposition of everolimus-eluting polymeric bioresorbable scaffold and everolimus-eluting cobalt chromium metallic stent in human coronary arteries: sequential assessment with optical coherence tomography in ABSORB Japan trial. Eur Heart J Cardiovasc Imaging 2018; 19 (01) 59-66
  • 53 Taniwaki M, Radu MD, Zaugg S. et al. Mechanisms of very late drug-eluting stent thrombosis assessed by optical coherence tomography. Circulation 2016; 133 (07) 650-660
  • 54 Soeda T, Uemura S, Park SJ. et al. Incidence and clinical significance of poststent optical coherence tomography findings: one-year follow-up study from a multicenter registry. Circulation 2015; 132 (11) 1020-1029
  • 55 Choi SY, Witzenbichler B, Maehara A. et al. Intravascular ultrasound findings of early stent thrombosis after primary percutaneous intervention in acute myocardial infarction: a Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) substudy. Circ Cardiovasc Interv 2011; 4 (03) 239-247
  • 56 Hong YJ, Jeong MH, Choi YH. et al. Impact of tissue prolapse after stent implantation on short- and long-term clinical outcomes in patients with acute myocardial infarction: an intravascular ultrasound analysis. Int J Cardiol 2013; 166 (03) 646-651
  • 57 Prati F, Romagnoli E, Gatto L. et al. Clinical impact of suboptimal stenting and residual intrastent plaque/thrombus protrusion in patients with acute coronary syndrome: the CLI-OPCI ACS Substudy (Centro per la Lotta Contro L'Infarto-Optimization of Percutaneous Coronary Intervention in Acute Coronary Syndrome). Circ Cardiovasc Interv 2016; 9 (12) e003726
  • 58 Kawamori H, Shite J, Shinke T. et al. Natural consequence of post-intervention stent malapposition, thrombus, tissue prolapse, and dissection assessed by optical coherence tomography at mid-term follow-up. Eur Heart J Cardiovasc Imaging 2013; 14 (09) 865-875
  • 59 Radu MD, Räber L, Heo J. et al. Natural history of optical coherence tomography-detected non-flow-limiting edge dissections following drug-eluting stent implantation. EuroIntervention 2014; 9 (09) 1085-1094
  • 60 Gonzalo N, Escaned J, Alfonso F. et al. Morphometric assessment of coronary stenosis relevance with optical coherence tomography: a comparison with fractional flow reserve and intravascular ultrasound. J Am Coll Cardiol 2012; 59 (12) 1080-1089 Erratum in: J Am Coll Cardiol 2012;59(16):1491. Gonzalo, Nieve [corrected to Gonzalo, Nieves]; Fernández-Ortiz, Antonia [corrected to Fernández-Ortiz, Antonio]
  • 61 Shiono Y, Kitabata H, Kubo T. et al. Optical coherence tomography-derived anatomical criteria for functionally significant coronary stenosis assessed by fractional flow reserve. Circ J 2012; 76 (09) 2218-2225
  • 62 Zafar H, Ullah I, Dinneen K. et al. Evaluation of hemodynamically severe coronary stenosis as determined by fractional flow reserve with frequency domain optical coherence tomography measured anatomical parameters. J Cardiol 2014; 64 (01) 19-24
  • 63 Pawlowski T, Prati F, Kulawik T, Ficarra E, Bil J, Gil R. Optical coherence tomography criteria for defining functional severity of intermediate lesions: a comparative study with FFR. Int J Cardiovasc Imaging 2013; 29 (08) 1685-1691
  • 64 Reith S, Battermann S, Hellmich M, Marx N, Burgmaier M. Correlation between optical coherence tomography-derived intraluminal parameters and fractional flow reserve measurements in intermediate grade coronary lesions: a comparison between diabetic and non-diabetic patients. Clin Res Cardiol 2015; 104 (01) 59-70
  • 65 Reith S, Battermann S, Jaskolka A. et al. Relationship between optical coherence tomography derived intraluminal and intramural criteria and haemodynamic relevance as determined by fractional flow reserve in intermediate coronary stenoses of patients with type 2 diabetes. Heart 2013; 99 (10) 700-707
  • 66 Pyxaras SA, Tu S, Barbato E. et al. Quantitative angiography and optical coherence tomography for the functional assessment of nonobstructive coronary stenoses: comparison with fractional flow reserve. Am Heart J 2013; 166 (06) 1010-1018.e1
  • 67 Usui E, Yonetsu T, Kanaji Y. et al. Efficacy of optical coherence tomography-derived morphometric assessment in predicting the physiological significance of coronary stenosis: head-to-head comparison with intravascular ultrasound. EuroIntervention 2018; 13 (18) e2210-e2218
  • 68 Veselka J, Cadová P, Adla T, Zemánek D. Dual-source computed tomography angiography and intravascular ultrasound assessment of restenosis in patients after coronary stenting for bifurcation left main stenosis: a pilot study. Arch Med Sci 2012; 8 (03) 455-461
  • 69 Kang SJ, Mintz GS, Akasaka T. et al. Optical coherence tomographic analysis of in-stent neoatherosclerosis after drug-eluting stent implantation. Circulation 2011; 123 (25) 2954-2963
  • 70 Song L, Mintz GS, Yin D. et al. Characteristics of early versus late in-stent restenosis in second-generation drug-eluting stents: an optical coherence tomography study. EuroIntervention 2017; 13 (03) 294-302
  • 71 Koskinas KC, Nakamura M, Räber L. et al. Current use of intracoronary imaging in interventional practice - results of a European Association of Percutaneous Cardiovascular Interventions (EAPCI) and Japanese Association of Cardiovascular Interventions and Therapeutics (CVIT) Clinical Practice Survey. Circ J 2018; 82 (05) 1360-1368