Abstract
High blood pressure remains a leading risk factor for cardiovascular death worldwide.
Optimal medical therapy and blood pressure control are important for the prevention
of cardiovascular and renal disease. The present review aims to provide an overview
about the innovations and novelties in the field of hypertension. First, new findings
concerning optimal blood pressure goals in high-risk patients are presented. Second,
developments of established medication regimes, particularly thiazide diuretic, as
well as innovations, the angiotensin receptor-neprilysin inhibitor, are reviewed.
Finally, pharmacological and non-pharmacological therapeutic options for resistant
hypertension are discussed, such as a recent study investigating spironolactone as
a 4th-line agent and renal denervation as a continuously evolving treatment option.
