J Neurol Surg B Skull Base 2021; 82(01): 096-099
DOI: 10.1055/s-0040-1722636
Typical Orbital Pathologies
Review Article

Not a Tumor-Nonspecific Orbital Inflammation

James A. Garrity
1  Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States
› Author Affiliations


Objective This study was aimed to illustrate the features and complexities of nonspecific orbital inflammation via discussion of two representative cases.

Design Present study is a retrospective case review.

Setting The study was conducted at a tertiary care medical center.

Participants Two patients with nonspecific orbital inflammation were participants of this retrospective study.

Main Outcome Measures Outcome of the study was disease-free patients and off all medications.

Results At follow-up, both patients are disease free and off all medications.

Conclusion Surgery plays a diagnostic and therapeutic role. While the clinical subtype is important for differential diagnosis and symptomatic treatment, the histologic subtype is similarly important. For inflammatory dacryoadenitis, surgery can be therapeutic. For extensive granulomatosis with polyangiitis, debulking surgery may allow better penetration of medications, especially rituximab.

Publication History

Publication Date:
02 February 2021 (online)

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