J Neurol Surg B Skull Base 2021; 82(01): 081-090
DOI: 10.1055/s-0040-1722635
Typical Orbital Pathologies
Review Article

Primary Malignant Orbital Tumors

Jacquelyn Laplant
1  Department of Ophthalmology, Tulane University, New Orleans, Louisiana, United States
Kimberly Cockerham
2  Stanford Department of Ophthalmology, Byers Eye Institute, Palo Alto, California, United States
› Institutsangaben


Objective Primary orbital malignancy is rare. Awareness of the characteristic clinical and imaging features is imperative for timely identification and management. Surgery remains an important diagnostic and treatment modality for primary orbital malignancy, but determining the optimal surgical approach can be challenging. The purpose of this article is to explore recent advances in the diagnosis, management, and surgical approaches for primary orbital malignancies.

Design In this review, the clinical presentation, imaging features, and medical and surgical management of primary orbital malignancies with representative cases will be discussed.

Setting Outpatient and inpatient hospital settings.

Participants Patients with diagnosed primary orbital malignancies.

Main Outcome Measures Descriptive outcomes.

Results Advancements in orbital imaging, microsurgical techniques, and multimodal therapy have improved the diagnosis and management of primary orbital malignancies. Special considerations for biopsy or resection are made based on the tumor's location, characteristics, nearby orbital structures, and goals of surgery. Minimally invasive techniques are supplanting traditional approaches to orbital surgery with less morbidity.

Conclusions Advances in imaging technologies and surgical techniques have facilitated the diagnosis and management of primary orbital malignancies. Evolution toward less invasive orbital surgery with focus on preservation and restoration of function is underway.


18. Februar 2021 (online)

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany