CC BY-NC-ND 4.0 · Asian Journal of Oncology 2021; 07(02): 064-075
DOI: 10.1055/s-0040-1722380
Original Article

Integrative Treatment of Lung Cancer Patients: Observational Study of 57 Cases

Lorenzo Anelli
1   Integrative Oncology Ambulatory, Nuova Villa Claudia, Rome, Italy
2   ARTOI, Rome, Italy
Alessia Di Nardo
2   ARTOI, Rome, Italy
Massimo Bonucci
1   Integrative Oncology Ambulatory, Nuova Villa Claudia, Rome, Italy
2   ARTOI, Rome, Italy
› Author Affiliations


Introduction A retrospective clinical study was performed to identify the characteristics of patients with lung cancer treated with integrative cancer treatment in addition to conventional medicine.

Materials and Methods We reviewed medical records for lung cancer patients who visited a single integrative setting in Rome, Italy. A total of 57 patients were included, and the majority had advanced-stage cancer. All of them underwent integrative therapy with nutrition and phytotherapy indications. The diet was designed to reduce most of possible factors promoting cancer proliferation, inflammation, and obesity. Foods with anti-inflammatory, prebiotic, antioxidant, and anticancer properties had been chosen. Herbal supplements with known effects on lung cancer were prescribed. In particular, astragal, apigenine, fucosterol, polydatin, epigallocatechin gallate, cannabis, curcumin, and inositol were used. Furthermore, medical mushrooms and other substances were used to improve the immune system and to reduce chemotherapy side effects. Five key parameters have been evaluated for 2 years starting at the first surgery: nutritional status, immune status, discontinuation of therapy, quality of life, and prognosis of the disease.

Results A relevant improvement in parameters relative to nutritional status, immune status, and quality of life has been observed after integrative therapy compared with the same parameters at the first medical visit before starting such approach.

Conclusion The results suggest that integrative therapy may have benefits in patients with lung cancer. Even though there are limitations, the study suggests that integrative therapy could improve nutritional status and quality of life, with possible positive effect on overall survival.

Publication History

Article published online:
14 April 2021

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