CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2022; 11(01): 083-085
DOI: 10.1055/s-0040-1721561
Short Communication

Concurrent Inverted Papilloma and Squamous Cell Carcinoma with Intradural Extension Presenting with Frontal Lobe Syndrome

Abdul Jaleel
1   Department of Neurosurgery, Government Medical College, Kozhikode, Kerala, India
,
V. M. Pavithran
1   Department of Neurosurgery, Government Medical College, Kozhikode, Kerala, India
,
Shanavas Cholakkal
1   Department of Neurosurgery, Government Medical College, Kozhikode, Kerala, India
,
Vineeth Kadangot Kuthampulli
1   Department of Neurosurgery, Government Medical College, Kozhikode, Kerala, India
› Author Affiliations
Funding None.

Abstract

Inverted papilloma is an uncommon tumor mostly arising from the lateral wall of the nasal cavity and displays a benign but locally aggressive behavior. Intracranial extension is an extremely rare presentation of inverted papilloma. Extension occurs either as a benign lesion or due to malignant transformation. We report a case of concurrent inverted papilloma and squamous cell carcinoma presenting with epistaxis and recent-onset altered behavior and memory impairment. After literature review of similar cases having inverted papilloma with intracranial extension, we could identify a total of 12 cases, most of which were recurrences of a primary inverted papilloma that were resected before extension into the cranial cavity. Most cases were of extradural extension, and intradural spread resulted in poor prognosis on follow-up. Concurrent inverted papilloma and squamous cell carcinoma extending into the anterior cranial fossa and frontal lobe is a very rare clinical entity and can present as frontal lobe syndrome.



Publication History

Article published online:
01 March 2021

© 2021. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Melroy CT, Senior BA. Benign sinonasal neoplasms: a focus on inverting papilloma. Otolaryngol Clin North Am 2006; 39 (03) 601-617 x
  • 2 Buchwald C, Franzmann MB, Jacobsen GK, Lindeberg H. Human papillomavirus (HPV) in sinonasal papillomas: a study of 78 cases using in situ hybridization and polymerase chain reaction. Laryngoscope 1995; 105 (01) 66-71
  • 3 Vrabec DP. The inverted Schneiderian papilloma: a 25-year study. Laryngoscope 1994; 104 (05) Pt 1 582-605
  • 4 Lawson W, Le J Benger, Som P, Bernard PJ, Biller HF. Inverted papilloma: an analysis of 87 cases. Laryngoscope 1989; 99 (11) 1117-1124
  • 5 Tomazic PV, Stammberger H, Habermann W. et al. Aggressive inverted papilloma with intracranial invasion and short malignization time. Skull Base Rep 2011; 1 (02) 111-114
  • 6 Anari S, Carrie S. Sinonasal inverted papilloma: narrative review. J Laryngol Otol 2010; 124 (07) 705-715
  • 7 Ridder GJ, Behringer S, Kayser G, Pfeiffer J. Malignome auf dem Boden invertierter Papillome der Nase und Nasennebenhöhlen. Laryngorhinootologie 2008; 87 (11) 783-790
  • 8 Andersen PJ, Kjeldsen AD, Pedersen AT. Treatment of inverted papilloma with endonasal endoscopic sinus surgery [in Danish]. Ugeskr Laeger 2002; 164 (37) 4283-4287