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CC BY-NC-ND 4.0 · J Lab Physicians 2020; 12(03): 219-221
DOI: 10.1055/s-0040-1720942
Case Report

Abiotrophia defectiva as a Rare Causative Agent of Periprosthetic Total Knee Arthroplasty Infections: A Case Report and Literature Review

Emre Kocazeybek
1   Department of Orthopedics and Traumatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
,
Mehmet Demirel
1   Department of Orthopedics and Traumatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
,
Mehmet Ersin
1   Department of Orthopedics and Traumatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
,
Omer Naci Ergin
1   Department of Orthopedics and Traumatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
,
Betul Sadic
2   Department of Infectious Diseases, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
,
Serap Simsek Yavuz
2   Department of Infectious Diseases, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
,
Mehmet Asik
1   Department of Orthopedics and Traumatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
› Author Affiliations Financial support This study received no financial support.
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Abstract

We present a case of Abiotrophia defectiva in a prosthetic knee infection following total knee replacement for the first time. A 69-year-old female was prediagnosed with prosthetic knee infection, and a two-stage revision arthroplasty was applied. A. defectiva was cultured by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) from the synovial fluid aspirates. Penicillin G and gentamicin had been administered. One year postoperatively, a scintigraphy showed no recurrence. A. defectiva may be missed in culture negative patients with knee or hip arthroplasty. They should be carefully evaluated if they have undergone recent dental procedures.

Keywords

Abiotrophia defectiva - osteoarticular infections - MALDI-TOF MS


Publication History

Article published online:
23 November 2020

© 2020. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Gupta P, Agstam S, Angrup A, Manoj RK, Kanaujia R, Ray P. Infective endocarditis caused by Abiotrophia defectiva presenting as anterior mitral leaflet perforation mimicking cleft anterior mitral leaflet. J Family Med Prim Care 2020; 9 (02) 1229-1231
    CrossrefPubMedGoogle Scholar
  • 2 Chroboczek T, Le Scanff J, David G. First case of Abiotophia defectiva infectious endocarditis treated with a combination of amoxicillin and daptomycin. J Chemother 2020; (e-pub ahead of print) DOI: 10.1080/1120009X.2020.1734163.
    CrossrefPubMedGoogle Scholar
  • 3 Elashery AR, Stratidis J, Patel AD. Double-valve heart disease and glomerulonephritis consequent to Abiotrophia defectiva endocarditis. Tex Heart Inst J 2020; 47 (01) 35-37
    CrossrefPubMedGoogle Scholar
  • 4 Tooley TR, Siljander MP, Hubers M. Development of a periprosthetic joint infection by Abiotrophia defectiva years after total knee arthroplasty. Arthroplast Today 2019; 5 (01) 49-51
    CrossrefPubMedGoogle Scholar
  • 5 Baddour LM, Wilson WR, Bayer AS. et al. American Heart Association Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and Stroke Council. Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: A Scientific Statement for Healthcare Professionals from the American Heart Association. Circulation 2015; 132 (15) 1435-1486
    CrossrefPubMedGoogle Scholar
  • 6 Cassir N, Grillo JC, Argenson JN, Drancourt M, Levy PY. Abiotrophia defectiva knee prosthesis infection: a case report. J Med Case Reports 2011; 5: 438
    CrossrefPubMedGoogle Scholar
  • 7 Ince A, Tiemer B, Gille J, Boos C, Russlies M. Total knee arthroplasty infection due to Abiotrophia defectiva . J Med Microbiol 2002; 51 (10) 899-902
    CrossrefPubMedGoogle Scholar
  • 8 Rozemeijer W, Jiya TU, Rijnsburger M, Heddema E, Savelkoul P, Ang W. Abiotrophia defectiva infection of a total hip arthroplasty diagnosed by 16S rRNA gene sequencing. Diagn Microbiol Infect Dis 2011; 70 (01) 142-144
    CrossrefPubMedGoogle Scholar
  • 9 Giannakopoulos K, Zompolou C, Behnes M, Elmas E, Borggrefe M, Akin I. Infective endocarditis - A word of caution on non-typical bacteria. Eur Rev Med Pharmacol Sci 2016; 20 (22) 4782-4785
    PubMedGoogle Scholar
  • 10 Holler JG, Pedersen LK, Calum H. et al. Using MALDI-TOF mass spectrometry as a rapid and accurate diagnostic tool in infective endocarditis: a case report of a patient with mitral valve infective endocarditis caused by Abiotrophia defectiva . Scand J Infect Dis 2011; 43 (03) 234-237
    CrossrefPubMedGoogle Scholar
  • 11 Berbari EF, Osmon DR, Carr A. et al. Dental procedures as risk factors for prosthetic hip or knee infection: a hospital-based prospective case-control study. Clin Infect Dis 2010; 50 (01) 8-16
    CrossrefPubMedGoogle Scholar
  • 12 Rudrappa M, Kokatnur L. Infective endocarditis due to Abiotrophia defectiva and its feared complications in an immunocompetent person: rare, but real. J Glob Infect Dis 2017; 9 (02) 79-81
    CrossrefPubMedGoogle Scholar