CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2021; 11(01): 01-07
DOI: 10.1055/s-0040-1718848
Review Article

Comorbidities in Patients with COVID-19 and Their Impact on the Severity of the Disease

Shahid Bashir
1  Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia
,
Sadaf Moneeba
2  Department of Bioinformatics and Biotechnology, International Islamic University Islamabad, Islamabad, Pakistan
,
Alaa Alghamdi
3  King Fahad University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
,
Fouad Alghamdi
1  Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia
,
Asim Niaz
1  Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia
,
Hadeel Anan
1  Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia
,
Imdad Kaleem
4  Department of Bioinformatics and Biosciences, COMSATS University (CUI), Islamabad, Pakistan
› Author Affiliations

Abstract

Infection with COVID-19 is associated with significant morbidity, especially in patients with chronic medical conditions. At least one-fifth of cases require supportive care in intensive care units, which have limited availability in most developing countries. A literature search was conducted on PubMed, Medline, Scopus, Embase, and Google Scholar to find articles published by May 7, 2020 on the role of comorbidities in patients with COVID-19 and the impact of comorbidities on the disease. This review highlighted that patients with comorbidities are more likely to experience severe disease than those with no other conditions; that is, comorbidities correlated with greater disease severity in patients with COVID-19. Proper screening of COVID-19 patients should include careful inquiries into their medical history; this will help healthcare providers identify patients who are more likely to develop serious disease or experience adverse outcomes. Better protection should also be given to patients with COVID-19 and comorbidities upon confirmation of the diagnosis. This literature review showed that the comorbidities most often associated with more severe cases of COVID-19 are hypertension, cardiovascular disease, and diabetes. Individuals with these comorbidities should adopt restrictive measures to prevent exposure to COVID-19, given their higher risk of severe disease.



Publication History

Publication Date:
16 October 2020 (online)

© 2020. Nitte University (Deemed to be University). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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