CC BY-NC-ND 4.0 · International Journal of Epilepsy 2020; 6(02): 54-58
DOI: 10.1055/s-0040-1718787
Original Article

Quality of Life Assessment in Pediatric Epilepsy

Sujana Shakya
1  Department of Pharmacy, Kathmandu University, Dhulikhel, Nepal
Rajani Shakya
1  Department of Pharmacy, Kathmandu University, Dhulikhel, Nepal
Prithuja Poudel
2  Dhulikhel Hospital, Kathmandu University Teaching Hospital, Dhulikhel, Nepal
Ashwinee Kumar Shrestha
1  Department of Pharmacy, Kathmandu University, Dhulikhel, Nepal
› Author Affiliations


Objectives Quality of life (QOL) is an accepted health outcome measure in clinical practice. This study was performed to assess QOL in pediatric epilepsy patients and identify demographic and clinical factors influencing it.

Materials and Methods A cross-sectional study was conducted in the outpatient pediatric department of Dhulikhel Hospital, a tertiary care teaching hospital in Nepal. Parents or caretakers of children receiving one or more antiepileptic drugs were interviewed using QOL childhood epilepsy questionnaire comprising 91 items with seven domains and 16 subscales. All the individual subscales of the questionnaire were found to be compromised with least score on QOL and general health item. Compromised social, physical, psychological, emotional, cognitive as well as behavioral domains were also identified.

Results QOL was found to be more impaired in older children and in those from rural areas. They had significant linguistic impairment and lower level of self-esteem. Overall QOL was found to be compromised more in patients with generalized than with focal epilepsy. Seizure frequency and polytherapy were the most important factors influencing overall QOL.

Conclusion Despite taking appropriate antiepileptic drugs, epilepsy was found to be detrimental to QOL of patients. Hence, QOL assessment should be an important part of epilepsy management protocol.

Publication History

Publication Date:
27 October 2020 (online)

© 2020. Indian Epilepsy Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

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