Subscribe to RSS
Quality of Life Assessment in Pediatric Epilepsy
Objectives Quality of life (QOL) is an accepted health outcome measure in clinical practice. This study was performed to assess QOL in pediatric epilepsy patients and identify demographic and clinical factors influencing it.
Materials and Methods A cross-sectional study was conducted in the outpatient pediatric department of Dhulikhel Hospital, a tertiary care teaching hospital in Nepal. Parents or caretakers of children receiving one or more antiepileptic drugs were interviewed using QOL childhood epilepsy questionnaire comprising 91 items with seven domains and 16 subscales. All the individual subscales of the questionnaire were found to be compromised with least score on QOL and general health item. Compromised social, physical, psychological, emotional, cognitive as well as behavioral domains were also identified.
Results QOL was found to be more impaired in older children and in those from rural areas. They had significant linguistic impairment and lower level of self-esteem. Overall QOL was found to be compromised more in patients with generalized than with focal epilepsy. Seizure frequency and polytherapy were the most important factors influencing overall QOL.
Conclusion Despite taking appropriate antiepileptic drugs, epilepsy was found to be detrimental to QOL of patients. Hence, QOL assessment should be an important part of epilepsy management protocol.
27 October 2020 (online)
© 2020. Indian Epilepsy Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
- 1 Leonardi M, Ustun TB. The global burden of epilepsy. Epilepsia 2002; 43 (Suppl. 06) 21-25
- 2 World Health Organization. International Classification of Functioning, Disability, and Health. Geneva: WHO; 2001
- 3 Ronen GM, Streiner DL, Rosenbaum P. Health-related quality of life in childhood epilepsy: moving beyond ‘seizure control with minimal adverse effects’. Health Qual Life Outcomes 2003; 1 (01) 36
- 4 Sabaz M, Cairns DR, Lawson JA, Nheu N, Bleasel AF, Bye AME. Validation of a new quality of life measure for children with epilepsy. Epilepsia 2000; 41 (06) 765-774
- 5 Tavakol M, Dennick R. Making sense of Cronbach’s alpha. Int J Med Educ 2011; 2: 53-55
- 6 Gambhir SK, Kumar V, Singhi PD, Goel RC. Public awareness, understanding & attitudes toward epilepsy. Indian J Med Res 1995; 102: 34-38
- 7 Devinsky O, Westbrook L, Cramer J, Glassman M, Perrine K, Camfield C. Risk factors for poor health-related quality of life in adolescents with epilepsy. Epilepsia 1999; 40 (12) 1715-1720
- 8 Nadkarni J, Jain A, Dwivedi R. Quality of life in children with epilepsy. Ann Indian Acad Neurol 2011; 14 (04) 279-282
- 9 Caplan R, Siddarth P, Vona P. et al. Language in pediatric epilepsy. Epilepsia 2009; 50 (11) 2397-2407
- 10 Aggarwal A, Datta V, Thakur LC. Quality of life in children with epilepsy. Indian Pediatr 2011; 48 (11) 893-896
- 11 Pal DK, Chaudhury G, Sengupta S, Das T. Social integration of children with epilepsy in rural India. Soc Sci Med 2002; 54 (12) 1867-1874