Novel Coronavirus: What to Learn from a Microbiologist?
In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) was declared in Wuhan, city of China. Later on, the World Health Organization declared COVID-19 as a pandemic on March 11, 2020. The clinical course of the disease ranges from asymptomatic cases to fatal severe respiratory illness. Various laboratory tests are available for the diagnosis of disease. The gold standard test is real-time PCR (polymerase chain reaction), whereas antigen testing can be used as a point-of-care test. Antibody detection by ELISA (enzyme-linked immunosorbent assay) can be used for the surveillance of the immune response.
15 October 2020 (online)
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- 1 Centers for Disease Control and Prevention. Initial Public Health Response and Interim Clinical Guidance for the 2019 Novel Coronavirus Outbreak — United States, December 31, 2019– February 4, 2020. Available at: https://www.cdc.gov/mmwr/volumes/69/wr/mm6905e1.htm?s_cid=mm6905%20e1_w
- 2 World Health Organization. Pneumonia of cause – China. Available at: https://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/#:~:text=On%2031%20December%202019%2C%20the,the%20national%20authorities%20in%20China.
- 3 World Health Organization. Coronavirus Disease (COVID-19) Dashboard. Available at: https://covid19.who.int/
- 4 Centers for Disease Control and Prevention. Coronavirus (COVID-19). Available at: https://www.cdc.gov/coronavirus/2019-ncov/index.html
- 5 Guo YR, Cao QD, Hong ZS. et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. Mil Med Res 2020; 7 (01) 11
- 6 Cascella M, Rajnik M, Cuomo A. et al. Features, evaluation and treatment coronavirus (COVID-19). In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing; 2020
- 7 Pasomsub E, Watcharananan SP, Boonyawat K. et al. Saliva sample as a non-invasive specimen for the diagnosis of coronavirus disease 2019: a cross-sectional study. Clin Microbiol Infect 2020; (e-pub ahead of print) DOI: 10.1016/j.cmi.2020.05.001.