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Open Access
CC BY 4.0 · Rev Bras Ginecol Obstet 2020; 42(12): 800-804
DOI: 10.1055/s-0040-1718444
Original Article
Obstetrics

Retrospective Evaluation of Patients Treated for Ectopic Pregnancy: Experience of a Tertiary Center

Autoren

  • Özge Kömürcü Karuserci 

    1   Obstetrics and Gynecology Department, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey

  • Seyhun Sucu 

    1   Obstetrics and Gynecology Department, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
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Abstract

Objective In recent years, there has been an increase in the incidence of ectopic pregnancies; therefore, it is important for tertiary centers to report their approaches and outcomes to expand and improve treatment modalities. The aim of the present study was to evaluate the general characteristics, treatment and outcomes of cases diagnosed with ectopic pregnancy.

Methods In total, 432 patients treated for ectopic pregnancy between February 2016 and June 2019 were retrospectively evaluated.

Results Overall, 370 patients had tubal pregnancy, 32 had cesarean scar pregnancy, 18 had pregnancy of unknown location, 6 had cervical pregnancy, and 6 had interstitial pregnancy. The most important risk factors were advanced age (> 35 years; prevalence: 31.2%) and smoking (prevalence: 27.1%). Thirty patients who did not have any symptoms of rupture and whose human chorionic gonadotropin (β-hCG) levels were ≤ 200 mIU/ml were followed-up with expectant management, while 316 patients whose β-hCG levels were between 1,500 mIU/ml and 5,000 mIU/ml did not have an intrauterine gestational sac on the transvaginal or abdominal ultrasound, did not demonstrate findings of rupture, and were treated with a systemic multi-dose methotrexate treatment protocol. In total, 24 patients who did not respond to the medical treatment, 20 patients whose β-hCG levels were > 5,000 mIU/ml, 16 patients who had shown symptoms of rupture at the initial presentation, and 6 patients diagnosed with interstitial pregnancy underwent surgery. Patients with cervical and scar pregnancies underwent ultrasound-guided curettage, and no additional treatment was needed.

Conclusion The fertility status of the patients, the clinical and laboratory findings, and the levels of β-hCG are the factors that must be considered in planning the appropriate treatment.

Keywords

ectopic pregnancy - treatment - methotrexate - surgery - expectant management

Contributions

All authors participated in the conception and design of the present study; in the analysis and interpretation of data; in the draft or revision of the manuscript; and they have approved the manuscript as submitted. All authors are responsible for the reported research.




Publikationsverlauf

Eingereicht: 20. März 2020

Angenommen: 12. August 2020

Artikel online veröffentlicht:
21. Dezember 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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