Radiation-Induced Malignant Peripheral Nerve Sheath Tumor of the Vagus Nerve Following Radiation Treatment of Cervical Paraganglioma

Abstract

Radiation-induced sarcoma is a known but rare complication of radiation treatment for skull base paraganglioma. We present the cases of a female patient with multiple paraganglioma syndrome treated with external beam radiation treatment who presented 4 years later with a malignant peripheral nerve sheath tumor of the vagus nerve.

Keywords

paraganglioma - radiation - vagus nerve - malignant peripheral nerve sheath tumor - radiation-induced sarcoma - glomus vagale

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the Declaration of Helsinki 1964 and its later amendments or comparable ethical standards.

Patient Consent

The patient's next of kin has given consent for submission of this case report.

Publikationsverlauf

Eingereicht: 16. März 2020

Angenommen: 02. September 2020

Artikel online veröffentlicht:
31. Dezember 2020

• References

• 1 Galland-Girodet S, Maire JP, De-Mones E. et al. The role of radiation therapy in the management of head and neck paragangliomas: impact of quality of life versus treatment response. Radiother Oncol 2014; 111 (03) 463-467
• 2 Gilbo P, Morris CG, Amdur RJ. et al. Radiotherapy for benign head and neck paragangliomas: a 45-year experience. Cancer 2014; 120 (23) 3738-3743
• 3 Liscak R, Urgosik D, Chytka T. et al. Leksell Gamma Knife radiosurgery of the jugulotympanic glomus tumor: long-term results. J Neurosurg 2014; 121 (Suppl): 198-202
• 4 Cole JM, Beiler D. Long-term results of treatment for glomus jugulare and glomus vagale tumors with radiotherapy. Laryngoscope 1994; 104 (12) 1461-1465
• 5 Hansen HS, Thomsen KA. Radiotherapy in glomus tumours (paragangliomas). A 25 year-review. Acta Otolaryngol Suppl 1988; 449: 151-154
• 6 Jackson AW, Koshiba R. Treatment of glomus jugulare tumours by radiotherapy. Proc R Soc Med 1974; 67 (04) 267-270
• 7 Krych AJ, Foote RL, Brown PD, Garces YI, Link MJ. Long-term results of irradiation for paraganglioma. Int J Radiat Oncol Biol Phys 2006; 65 (04) 1063-1066
• 8 Lalwani AK, Jackler RK, Gutin PH. Lethal fibrosarcoma complicating radiation therapy for benign glomus jugulare tumor. Am J Otol 1993; 14 (04) 398-402
• 9 Lustig LR, Jackler RK, Lanser MJ. Radiation-induced tumors of the temporal bone. Am J Otol 1997; 18 (02) 230-235
• 10 Na AF, Lai LT, Kaye AH. Radiation induced brainstem glioblastoma in a patient treated for glomus jugulare tumour. J Clin Neurosci 2015; 22 (01) 219-221
• 11 Preissig SH, Bohmfalk GL, Reichel GW, Smith MT. Anaplastic astrocytoma following radiation for a glomus jugular tumor. Cancer 1979; 43 (06) 2243-2247
• 12 Cahan WG, Woodard HQ, Higinbotham NL, Stewart FW, Coley BL. Sarcoma arising in irradiated bone; report of 11 cases. Cancer 1948; 1 (01) 3-29
• 13 Mark RJ, Bailet JW, Poen J. et al. Postirradiation sarcoma of the head and neck. Cancer 1993; 72 (03) 887-893
• 14 Williams L, Tmanova L, Mydlarz WK. et al. Radiation-associated sarcoma of the neck: case series and systematic review. Ann Otol Rhinol Laryngol 2018; 127 (10) 735-740
• 15 Wong WW, Hirose T, Scheithauer BW, Schild SE, Gunderson LL. Malignant peripheral nerve sheath tumor: analysis of treatment outcome. Int J Radiat Oncol Biol Phys 1998; 42 (02) 351-360
• 16 Berrington de Gonzalez A, Gilbert E, Curtis R. et al. Second solid cancers after radiation therapy: a systematic review of the epidemiologic studies of the radiation dose-response relationship. Int J Radiat Oncol Biol Phys 2013; 86 (02) 224-233
• 17 Kumar S. Second malignant neoplasms following radiotherapy. Int J Environ Res Public Health 2012; 9 (12) 4744-4759
• 18 Rosko AJ, Birkeland AC, Chinn SB. et al. Survival and margin status in head and neck radiation-induced sarcomas and de novo sarcomas. Otolaryngol Head Neck Surg 2017; 157 (02) 252-259
• 19 Toda K, Shibuya H, Hayashi K, Ayukawa F. Radiation-induced cancer after radiotherapy for non-Hodgkin's lymphoma of the head and neck: a retrospective study. Radiat Oncol 2009; 4: 21
• 20 Little MP. Evidence for dose and dose rate effects in human and animal radiation studies. Ann ICRP 2018; 47 (3-4): 97-112
• 21 Kuttesch Jr JF, Wexler LH, Marcus RB. et al. Second malignancies after Ewing's sarcoma: radiation dose-dependency of secondary sarcomas. J Clin Oncol 1996; 14 (10) 2818-2825
• 22 Rubino C, Shamsaldin A, Lê MG. et al. Radiation dose and risk of soft tissue and bone sarcoma after breast cancer treatment. Breast Cancer Res Treat 2005; 89 (03) 277-288
• 23 Genç A, Bicer A, Abacioglu U, Peker S, Pamir MN, Kilic T. Gamma Knife radiosurgery for the treatment of glomus jugulare tumors. J Neurooncol 2010; 97 (01) 101-108
• 24 Guss ZD, Batra S, Limb CJ. et al. Radiosurgery of glomus jugulare tumors: a meta-analysis. Int J Radiat Oncol Biol Phys 2011; 81 (04) e497-e502
• 25 Ibrahim R, Ammori MB, Yianni J, Grainger A, Rowe J, Radatz M. Gamma Knife radiosurgery for glomus jugulare tumors: a single-center series of 75 cases. J Neurosurg 2017; 126 (05) 1488-1497
• 26 Marchetti M, Pinzi V, Tramacere I, Bianchi LC, Ghielmetti F, Fariselli L. Radiosurgery for paragangliomas of the head and neck: another step for the validation of a treatment paradigm. World Neurosurg 2017; 98: 281-287
• 27 Winford TW, Dorton LH, Browne JD, Chan MD, Tatter SB, Oliver ER. Stereotactic radiosurgical treatment of glomus jugulare tumors. Otol Neurotol 2017; 38 (04) 555-562
• 28 Guha A, Musil Z, Vicha A. et al. A systematic review on the genetic analysis of paragangliomas: primarily focused on head and neck paragangliomas. Neoplasma 2019; 66 (05) 671-680
• 29 Burnichon N, Rohmer V, Amar L. et al; PGL.NET network. The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. J Clin Endocrinol Metab 2009; 94 (08) 2817-2827