Geburtshilfe Frauenheilkd 2020; 80(10): e218
DOI: 10.1055/s-0040-1718218
Poster
Mittwoch, 7.10.2020
Gynäkologische Onkologie IV

Management of patients with STIC lesions in Germany – First results of a questionnaire based AGO Ovar survey

J van der Ven
1   Universitätsmedizin Mainz, Klinik und Poliklinik für Geburtshilfe und Frauengesundheit, Mainz, Deutschland
,
V Linz
1   Universitätsmedizin Mainz, Klinik und Poliklinik für Geburtshilfe und Frauengesundheit, Mainz, Deutschland
,
R Schwab
1   Universitätsmedizin Mainz, Klinik und Poliklinik für Geburtshilfe und Frauengesundheit, Mainz, Deutschland
,
S Komoss
2   Universitätsklinik Tübingen, Department für Frauengesundheit, Tübingen, Deutschland
3   Arbeitsgemeinschaft Gynäkologische Onkologie e.V., Kommission Ovar, Taufkirchen, Deutschland
,
B Schmalfeldt
3   Arbeitsgemeinschaft Gynäkologische Onkologie e.V., Kommission Ovar, Taufkirchen, Deutschland
4   Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Gynäkologie, Hamburg, Deutschland
,
J Sehouli
3   Arbeitsgemeinschaft Gynäkologische Onkologie e.V., Kommission Ovar, Taufkirchen, Deutschland
5   Charité – Universitätsmedizin Berlin, Klinik für Gynäkologie mit Zentrum für onkologische Chirurgie, Berlin, Deutschland
,
A Hasenburg
1   Universitätsmedizin Mainz, Klinik und Poliklinik für Geburtshilfe und Frauengesundheit, Mainz, Deutschland
3   Arbeitsgemeinschaft Gynäkologische Onkologie e.V., Kommission Ovar, Taufkirchen, Deutschland
,
MJ Battista
1   Universitätsmedizin Mainz, Klinik und Poliklinik für Geburtshilfe und Frauengesundheit, Mainz, Deutschland
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Objective Despite the growing understanding of the carcinogenesis of high-grade serous ovarian cancer and its precursor lesion serous tubal intraepithelial carcinoma (STIC), evidence based proven recommendations on the clinical management of patients with STIC lesion are lacking.

Material A questionnaire containing 23 multiple-choice questions was established to explore the experience with STIC patients and the diagnostical, surgical and histopathological approaches. 540 clinical directors of all German gynecological clinics were asked to participate in April 2020. SPSS was used for statistical analysis.

Results 131 out of 540 (24.3%) questionnaires were included. Most of the responders (45.8%) had treated one to three STIC patients so far. 76.0% of the participants perform opportunistic bilateral salpingectomies during other gynecological surgeries. Most of the participants (30.45%) started with the SEE-FIM protocol in 2017. It is used by 54.2% for prophylactic salpingectomies, by 28.1% for both prophylactic and opportunistic salpingectomies and by 17.7% for neither of both.

In premenopausal (postmenopausal) STIC patients the responders would perform a hysterectomy, bilateral salpingo-oophorectomy and affected side ovarectomy in 25.58% (54.65%), 24.42% (88.37%) and 50.0% (4.65%), respectively (all p-values < 0.001). Omentectomy, pelvic and para-aortic lymphadenectomy would be performed by 60.47% (63.95%), 9.30% (11.63%) and 9.30% (11.63%) survey participants in premenopausal (postmenopausal) STIC patients (all p-values >0.05). 58.8%, 2.4%, 37.6% of participants use the laparoscopic, transverse- or longitudinal laparotomic approach, respectively.

Conclusion This survey highlights significant inconsistency in the management of patients with STIC. Further studies are urgently warranted to elucidate the clinical impact and management of a STIC lesion.



Publication History

Article published online:
07 October 2020

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