CC BY-NC-ND 4.0 · AJP Rep 2020; 10(04): e347-e351
DOI: 10.1055/s-0040-1716733
Case Report

High Blood Pressure in a Urea Cycle Disorder: Case Report

Carolina Solé
1  Department of Neonatology, Gregorio Marañon Hospital, Madrid, Spain
María Arriaga
1  Department of Neonatology, Gregorio Marañon Hospital, Madrid, Spain
Elvira Cañedo
2  Department of Metabolism Diseases and Nutrition, Niño Jesús Hospital, Madrid, Spain
› Author Affiliations


Introduction Urea cycle disorders (UCDs) form a group of metabolic pathological conditions that might develop serious neurological consequences. Early diagnosis, before irreversible damage is established, is the most important prognostic and morbidity factor.

Case Report We present the case of a 5-day newborn with high blood pressure and respiratory distress. Diagnosis was type I citrullinemia. With appropriate citrullinemia guided-treatment blood pressure returned to normal.

Conclusion High blood pressure has been rarely described as a lead symptom for the debut of a UCD. We must take this into consideration as an early recognition and treatment of these disorders are of the utmost importance.

Authors' Contribution

C.S.D. wrote the manuscript. M.A.R. and E.C. reviewed and corrected the manuscript. All authors approved the final version.

Publication History

Received: 11 June 2020

Accepted: 15 June 2020

Publication Date:
07 October 2020 (online)

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