CC BY-NC-ND 4.0 · Am J Perinatol 2020; 37(12): 1283-1288
DOI: 10.1055/s-0040-1715839
Short Communication

Beyond the First Wave: Consequences of COVID-19 on High-Risk Infants and Families

Monica E. Lemmon
1   Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina
2   Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina
,
Ira Chapman
3   Division of Neonatology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia
,
William Malcolm
2   Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina
,
Kelli Kelley
4   Hand to Hold, Austin, Texas
,
Richard J. Shaw
5   Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California
,
Angelo Milazzo
2   Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina
,
C. Michael Cotten
2   Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina
,
Susan R. Hintz
6   Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California
› Institutsangaben
Funding M.E.L. is supported by the National Institutes of Neurological Disorders and Stroke (K23NS116453).

Abstract

The novel coronavirus disease 2019 (COVID-19) pandemic is affecting care for high-risk newborns in ways that will likely be sustained beyond the initial pandemic response. These novel challenges present an urgent imperative to understand how COVID-19 impacts parent, family, and infant outcomes. We highlight three areas that warrant targeted attention: (1) inpatient care: visitation policies, developmental care, and communication practices; (2) outpatient care: high-risk infant follow-up and early intervention programs; and (3) parent psychosocial distress: mental health, social support, and financial toxicity. Changes to care delivery in these areas provide an opportunity to identify and implement novel strategies to provide family-centered care during COVID-19 and beyond.

Key Points

  • The COVID-19 pandemic is influencing care delivery for high-risk newborns and their families.

  • Rapid changes to care delivery are likely to be sustained beyond the initial pandemic response.

  • We have an urgent imperative to understand how COVID-19 impacts infant, parent, and family outcomes.



Publikationsverlauf

Eingereicht: 20. Juli 2020

Angenommen: 27. Juli 2020

Artikel online veröffentlicht:
10. September 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 National registry for surveillance and epidemiology of perinatal COVID-19 infection.. Available at: https://services.aap.org/globalassets/sonpm/sonpmdatadictionaryregistry.pdf . Accessed August 3, 2020
  • 2 Mullins E. A global registry of women affected by COVID-19 in pregnancy and their babies, to guide treatment and prevention. London, UK: Imperial College Healthcare NHS Trust; 2020
  • 3 Della Gatta AN, Rizzo R, Pilu G, Simonazzi G. Coronavirus disease 2019 during pregnancy: a systematic review of reported cases. Am J Obstet Gynecol 2020; 223 (01) 36-41
  • 4 Di Mascio D, Khalil A, Saccone G. , et al. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM 2020; 2 (02) 100107
  • 5 Chen H, Guo J, Wang C. , et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet 2020; 395 (10226): 809-815
  • 6 Lamouroux A, Attie-Bitach T, Martinovic J, Leruez-Ville M, Ville Y. Evidence for and against vertical transmission for SARS-CoV-2 (COVID-19). Am J Obstet Gynecol 2020; 223 (01) 91.e1-91.e4
  • 7 Karimi-Zarchi M, Neamatzadeh H, Dastgheib SA. , et al. Vertical transmission of coronavirus disease 19 (COVID-19) from infected pregnant mothers to neonates: a review. Fetal Pediatr Pathol 2020; 39 (03) 246-250
  • 8 Vivanti AJ, Vauloup-Fellous C, Prevot S. , et al. Transplacental transmission of SARS-CoV-2 infection. Nat Commun 2020; 11 (01) 3572
  • 9 CPQCC/CMQCC. COVID-19 resources for maternal and infant health. CA Perinatal Programs. . Available at: https://www.caperinatalprograms.org/ Accessed August 3, 2020
  • 10 Boundy EO, Dastjerdi R, Spiegelman D. , et al. Kangaroo mother care and neonatal outcomes: a meta-analysis. Pediatrics 2016 137(01):
  • 11 Holditch-Davis D, White-Traut RC, Levy JA, O'Shea TM, Geraldo V, David RJ. Maternally administered interventions for preterm infants in the NICU: effects on maternal psychological distress and mother-infant relationship. Infant Behav Dev 2014; 37 (04) 695-710
  • 12 Johnston C, Campbell-Yeo M, Disher T. , et al. Skin-to-skin care for procedural pain in neonates. Cochrane Database Syst Rev 2017; 2: CD008435
  • 13 Karimi FZ, Sadeghi R, Maleki-Saghooni N, Khadivzadeh T. The effect of mother-infant skin to skin contact on success and duration of first breastfeeding: a systematic review and meta-analysis. Taiwan J Obstet Gynecol 2019; 58 (01) 1-9
  • 14 Lumbanraja SN. Influence of maternal factors on the successful outcome of kangaroo mother care in low birth-weight infants: A randomized controlled trial. J Neonatal Perinatal Med 2016; 9 (04) 385-392
  • 15 Nyqvist KH, Anderson GC, Bergman N. , et al; Expert Group of the International Network on Kangaroo Mother Care. State of the art and recommendations. Kangaroo mother care: application in a high-tech environment Acta Paediatr 2010; 99 (06) 812-819
  • 16 Sweeney S, Rothstein R, Visintainer P, Rothstein R, Singh R. Impact of kangaroo care on parental anxiety level and parenting skills for preterm infants in the neonatal intensive care unit. J Neonatal Nurs 2017; 23 (03) 151-158
  • 17 Athanasopoulou E, Fox JRE. Effects of kangaroo mother care on maternal mood and interaction patterns between parents and their preterm, low birth weight infants: a systematic review. Infant Ment Health J 2014; 35 (03) 245-262
  • 18 Bera A, Ghosh J, Singh AK, Hazra A, Mukherjee S, Mukherjee R. Effect of kangaroo mother care on growth and development of low birthweight babies up to 12 months of age: a controlled clinical trial. Acta Paediatr 2014; 103 (06) 643-650
  • 19 Franck LS, O'Brien K. The evolution of family-centered care: From supporting parent-delivered interventions to a model of family integrated care. Birth Defects Res 2019; 111 (15) 1044-1059
  • 20 Benzies KM, Magill-Evans JE, Hayden KA, Ballantyne M. Key components of early intervention programs for preterm infants and their parents: a systematic review and meta-analysis. BMC Pregnancy Childbirth 2013; 13 (01) (Suppl. 01) S10
  • 21 Evans T, Whittingham K, Sanders M, Colditz P, Boyd RN. Are parenting interventions effective in improving the relationship between mothers and their preterm infants?. Infant Behav Dev 2014; 37 (02) 131-154
  • 22 Lemmon ME, Donohue PK, Parkinson C, Northington FJ, Boss RD. Communication challenges in neonatal encephalopathy. Pediatrics 2016; 138 (03) e20161234
  • 23 Sabnis A, Fojo S, Nayak SS, Lopez E, Tarn DM, Zeltzer L. Reducing parental trauma and stress in neonatal intensive care: systematic review and meta-analysis of hospital interventions. J Perinatol 2019; 39 (03) 375-386
  • 24 Shaw RJ, John St. N, Lilo E. , et al. Prevention of traumatic stress in mothers of preterms: 6-month outcomes. Pediatrics 2014; 134 (02) e481-e488
  • 25 Horwitz SM, Leibovitz A, Lilo E. , et al. Does an intervention to reduce maternal anxiety, depression and trauma also improve mothers' perceptions of their preterm infants' vulnerability?. Infant Ment Health J 2015; 36 (01) 42-52
  • 26 MOD. NICU Family Online Education Series - COVID-19. March of Dimes. Available at: https://www.marchofdimes.org/nicufamilysupport/covid-19-online-nicu-family-education-series.aspx Accessed August 3, 2020
  • 27 Ernsting C, Stühmann LM, Dombrowski SU, Voigt-Antons JN, Kuhlmey A, Gellert P. Associations of health app use and perceived effectiveness in people with cardiovascular diseases and diabetes: population-based survey. JMIR Mhealth Uhealth 2019; 7 (03) e12179
  • 28 Clements KM, Barfield WD, Ayadi MF, Wilber N. Preterm birth-associated cost of early intervention services: an analysis by gestational age. Pediatrics 2007; 119 (04) e866-e874
  • 29 Spittle A, Orton J, Anderson PJ, Boyd R, Doyle LW. Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants. Cochrane Database Syst Rev 2015; (11) CD005495
  • 30 American Academy of Pediatrics Committee on Fetus and Newborn. Hospital discharge of the high-risk neonate. Pediatrics 2008; 122 (05) 1119-1126
  • 31 Wang CJ, McGlynn EA, Brook RH. , et al. Quality-of-care indicators for the neurodevelopmental follow-up of very low birth weight children: results of an expert panel process. Pediatrics 2006; 117 (06) 2080-2092
  • 32 Kuppala VS, Tabangin M, Haberman B, Steichen J, Yolton K. Current state of high-risk infant follow-up care in the United States: results of a national survey of academic follow-up programs. J Perinatol 2012; 32 (04) 293-298
  • 33 Greene M, Patra K. Part C early intervention utilization in preterm infants: opportunity for referral from a NICU follow-up clinic. Res Dev Disabil 2016; 53-54: 287-295
  • 34 Spittle A, Orton J, Anderson P, Boyd R, Doyle LW. Early developmental intervention programmes post-hospital discharge to prevent motor and cognitive impairments in preterm infants. Cochrane Database Syst Rev 2012; 12: CD005495
  • 35 McManus BM, Carle AC, Poehlmann J. Effectiveness of part C early intervention physical, occupational, and speech therapy services for preterm or low birth weight infants in Wisconsin, United States. Acad Pediatr 2012; 12 (02) 96-103
  • 36 Maitre NL, Burton VJ, Duncan AF. , et al. Network implementation of guideline for early detection decreases age at cerebral palsy diagnosis. Pediatrics 2020; 145 (05) e20192126
  • 37 Hintz SR, Gould JB, Bennett MV. , et al. Factors associated with successful first high-risk infant clinic visit for very low birth weight infants in California. J Pediatr 2019; 210: 91-98.e1
  • 38 Vohr B, McGowan E, Keszler L. , et al. Impact of a transition home program on rehospitalization rates of preterm infants. J Pediatr 2017; 181: 86-92.e1
  • 39 Liu Y, McGowan E, Tucker R, Glasgow L, Kluckman M, Vohr B. Transition home plus program reduces medicaid spending and health care use for high-risk infants admitted to the neonatal intensive care unit for 5 or more days. J Pediatr 2018; 200: 91-97.e3
  • 40 Nouri S, Khoong EC, Lyles CR, Karliner L. Addressing equity in telemedicine for chronic disease management during the COVID-19 pandemic. . Available at: https://catalyst.nejm.org/doi/pdf/10.1056/CAT.20.0123 . Accessed August 3, 2020
  • 41 Pew Research Center. Mobile fact sheet. Available at: http://www.pewinternet.org/fact-sheet/mobile/ . Accessed April 6, 2020
  • 42 Pew Research Center. Internet/broadband fact sheet. Available at: http://www.pewinternet.org/fact-sheet/internet-broadband/ . Accessed April 2, 2020
  • 43 Feeley N, Zelkowitz P, Cormier C, Charbonneau L, Lacroix A, Papageorgiou A. Posttraumatic stress among mothers of very low birthweight infants at 6 months after discharge from the neonatal intensive care unit. Appl Nurs Res 2011; 24 (02) 114-117
  • 44 Shaw RJ, Bernard RS, Storfer-Isser A, Rhine W, Horwitz SM. Parental coping in the neonatal intensive care unit. J Clin Psychol Med Settings 2013; 20 (02) 135-142
  • 45 Garel M, Dardennes M, Blondel B. Mothers' psychological distress 1 year after very preterm childbirth. Results of the EPIPAGE qualitative study. Child Care Health Dev 2007; 33 (02) 137-143
  • 46 Yildiz PD, Ayers S, Phillips L. The prevalence of posttraumatic stress disorder in pregnancy and after birth: a systematic review and meta-analysis. J Affect Disord 2017; 208: 634-645
  • 47 Shaw RJ, Deblois T, Ikuta L, Ginzburg K, Fleisher B, Koopman C. Acute stress disorder among parents of infants in the neonatal intensive care nursery. Psychosomatics 2006; 47 (03) 206-212
  • 48 Hall SL, Ryan DJ, Beatty J, Grubbs L. Recommendations for peer-to-peer support for NICU parents. J Perinatol 2015; 35 (Suppl. 01) S9-S13
  • 49 Kerr SM, McIntosh JB. Coping when a child has a disability: exploring the impact of parent-to-parent support. Child Care Health Dev 2000; 26 (04) 309-322
  • 50 Jarrett MH. Parent partners: a parent-to-parent support program in the NICU. Part II: Program implementation. Pediatr Nurs 1996; 22 (02) 142-144 , 149
  • 51 Nearing GB, Salas AA, Granado-Villar D, Chandler BD, Soliz A. Psychosocial parental support programs and short-term clinical outcomes in extremely low-birth-weight infants. J Matern Fetal Neonatal Med 2012; 25 (01) 89-93
  • 52 Lindsay JK, Roman L, DeWys M, Eager M, Levick J, Quinn M. Creative caring in the NICU: parent-to-parent support. Neonatal Netw 1993; 12 (04) 37-44
  • 53 Dennis CL, Hodnett E, Kenton L. , et al. Effect of peer support on prevention of postnatal depression among high risk women: multisite randomised controlled trial. BMJ 2009; 338: a3064
  • 54 Ahlund S, Clarke P, Hill J, Thalange NKS. Post-traumatic stress symptoms in mothers of very low birth weight infants 2-3 years post-partum. Arch Women Ment Health 2009; 12 (04) 261-264
  • 55 Horwitz SM, Storfer-Isser A, Kerker BD. , et al. A model for the development of mothers' perceived vulnerability of preterm infants. J Dev Behav Pediatr 2015; 36 (05) 371-380
  • 56 Greene MM, Rossman B, Meier P, Patra K. Elevated maternal anxiety in the NICU predicts worse fine motor outcome in VLBW infants. Early Hum Dev 2018; 116: 33-39
  • 57 Zelkowitz P, Na S, Wang T, Bardin C, Papageorgiou A. Early maternal anxiety predicts cognitive and behavioural outcomes of VLBW children at 24 months corrected age. Acta Paediatr 2011; 100 (05) 700-704
  • 58 Xie X, Xue Q, Zhou Y. , et al. Mental health status among children in home confinement during the coronavirus disease 2019 outbreak in Hubei Province, China. JAMA Pediatr 2020; (e-pub ahead of print) DOI: 10.1001/jamapediatrics.2020.1619.
  • 59 Brooks SK, Webster RK, Smith LE. , et al. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet 2020; 395 (10227): 912-920
  • 60 Wu P, Liu X, Fang Y. , et al. Alcohol abuse/dependence symptoms among hospital employees exposed to a SARS outbreak. Alcohol Alcohol 2008; 43 (06) 706-712
  • 61 Mihashi M, Otsubo Y, Yinjuan X, Nagatomi K, Hoshiko M, Ishitake T. Predictive factors of psychological disorder development during recovery following SARS outbreak. Health Psychol 2009; 28 (01) 91-100
  • 62 Jeong H, Yim HW, Song YJ. , et al. Mental health status of people isolated due to middle east respiratory syndrome. Epidemiol Health 2016; 38: e2016048
  • 63 Hawryluck L, Gold WL, Robinson S, Pogorski S, Galea S, Styra R. SARS control and psychological effects of quarantine, Toronto, Canada. Emerg Infect Dis 2004; 10 (07) 1206-1212