The Journal of Hip Surgery 2020; 4(03): 134-141
DOI: 10.1055/s-0040-1715130
Original Article

Mepivacaine Spinal Anesthesia Facilitates Shorter Lengths of Stay and Fewer Urinary Complications in Total Hip Arthroplasty Compared to Bupivacaine

Jonathan H. Shaw
1  Department of Orthopaedic Surgery, Henry Ford Health System, Detroit, Michigan
,
M. Chad Mahan
1  Department of Orthopaedic Surgery, Henry Ford Health System, Detroit, Michigan
,
Justin Jabara
2  School of Medicine, Wayne State University, Detroit, Michigan
,
Toufic R. Jildeh
1  Department of Orthopaedic Surgery, Henry Ford Health System, Detroit, Michigan
,
Jason J. Davis
1  Department of Orthopaedic Surgery, Henry Ford Health System, Detroit, Michigan
› Author Affiliations

Abstract

The purpose of this study was to compare the shorter-acting spinal anesthetic mepivacaine versus bupivacaine in total hip arthroplasty (THA). We retrospectively reviewed a prospectively collected database from a single surgeon's contemporary cohort of 311 consecutive patients undergoing primary THA. Primary outcomes were urinary retention, length of stay (LOS), neuraxial complications, pain control, and opioid consumption. Statistical analysis with univariate logistic regression was performed followed by a multivariate analysis controlling for multiple factors to evaluate the effect of anesthetic on primary outcomes. The univariate analysis demonstrated those with mepivacaine required less postoperative catheterization (0.0 vs. 5.7%, p = 0.009). Multivariate analysis exhibited that the mepivacaine group had a higher average opioid requirement (morphine equivalence [MEQ] 0.64 ± 0.22 vs. 1.17 ± 0.23; p < 0.001), similar average pain scores (visual analog scale 1.96 ± 0.24 vs. 2.65 ± 0.25), a lower LOS (0.90 ± 0.15 vs. 1.19 ± 0.15, p < 0.001), and an almost 10 times higher chance for a same-day discharge (odds ratio 9.67, 3.72–25.15, p < 0.001). There were no neuraxial complications in either group and no need for conversion to general anesthesia with the shorter-acting mepivacaine. Mepivacaine for spinal anesthesia with THA produced a significant improvement in recovery time with less urinary complications, a shorter LOS, and a higher chance of same-day discharge. Pain was well controlled in both groups with slightly increased pain and MEQ in the early postoperative period.



Publication History

Received: 03 January 2020

Accepted: 26 May 2020

Publication Date:
22 September 2020 (online)

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