Journal of Pediatric Neurology
DOI: 10.1055/s-0040-1714689
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Potential Role of Growth Hormone in a Pediatric Transient Ischemic Attack

David Farrier
1  Baylor College of Medicine, Houston, Texas, United States
,
2  Section of Pediatric Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States
,
Brittnie Bartlett
2  Section of Pediatric Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States
,
Farida Abid
2  Section of Pediatric Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States
› Author Affiliations
Further Information

Publication History

04 May 2020

24 June 2020

Publication Date:
05 August 2020 (online)

Abstract

Growth hormone (GH) is often prescribed in pediatric populations with short stature and is associated with several potential adverse events. One underrecognized potential adverse event is its effect on intracerebral vasculature, with concern for its ability to cause cerebrovascular accident. We present a pediatric case of presumed transient ischemic attack in the setting of chronic GH administration for idiopathic short stature syndrome. We propose potential pathogenic mechanisms for intracerebral vessel stenosis. We hope this case becomes a resource for clinicians and other healthcare providers when deciding whether or not to start GH in their young patients.

Informed Consent

Expressed and written consent was obtained by the patient's legal guardian, though no identifying information has been used.