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CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2020; 9(02): 122-126
DOI: 10.1055/s-0040-1714166
Review Article

Botulinum Toxin Injections as a Treatment of Postoperative Chronic Neck Pain Secondary to Cervical Spine Surgery

James Meiling 
1   Department of Internal Medicine, Medical City Weatherford, Weatherford, Texas, United States
,
Brandon Barndt
2   Department of Internal Medicine, Mercy Catholic Medical Center, Philadelphia, Pennsylvania, United States
,
George Raum 
3   Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, United States
,
David Schulze
1   Department of Internal Medicine, Medical City Weatherford, Weatherford, Texas, United States
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Abstract

Postoperative neck pain is a relatively common consequence of cervical spine surgeries such as anterior cervical discectomy with fusion and laminoplasty. Botulinum toxin injections are a relatively new treatment option to target muscle spasms, a possible cause of postoperative neck pain. This systematic review aims to evaluate the current literature highlighting the utilization of botulinum toxin for treating postoperative neck pain. The literature search resulted in one preliminary case–control trial, one case series and one case report. The use of Botox in these studies had promising benefits on postoperative neck pain, by reducing visual analog scores and improving objective measures of muscle tone such as cervical lordosis angle. While not seen in these studies, the use of botulinum toxin injections into the muscles of the region of the head, neck, and shoulder is not without risks such as focal muscle loss, joint instability, and respiratory and swallowing difficulty. With this in mind, while botulinum toxin may be a promising treatment for these patients, further well-designed studies are needed to further assess the treatments efficacy and safety in this patient population.

Keywords

postoperative neck pain - botulinum toxin - cervical spine surgery


Publikationsverlauf

Artikel online veröffentlicht:
26. August 2020

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  • References

  • 1 Finiels PJ, Batifol D. [Usefulness of botulinum toxin injections in the treatment of postoperative pain after cervical spine surgery: preliminary results]. Neurochirurgie 2010; 56 (05) 374-381
    CrossrefPubMedGoogle Scholar
  • 2 Finiels PJ, Batifol D. The interest of botulinum toxin in the treatment of cervical pain of different origins. In: Neuropathic Pain. Avid Science. 2019: 2-9
    Google Scholar
  • 3 Niezgoda JA, Hardin ST, Kubat N, Acompanado J. The management of intractable pain with adjuvant pulsed electromagnetic field therapy. Adv Skin Wound Care 2014; 27 (05) 205-209
    CrossrefPubMedGoogle Scholar
  • 4 Mohan A, Chang E. Decompression for botulinum toxin-exacerbated cervical myeloradiculopathy in the setting of congenital stenosis and Arnold-Chiari I malformation. Spinal Cord Ser Cases 2018; 4: 42
    CrossrefPubMedGoogle Scholar
  • 5 Hogan KA, Manning EL, Glaser JA. Progressive cervical kyphosis associated with botulinum toxin injection. South Med J 2006; 99 (08) 888-891
    CrossrefPubMedGoogle Scholar
  • 6 Ramachandran M, Eastwood DM. Botulinum toxin and its orthopaedic applications. J Bone Joint Surg Br 2006; 88 (08) 981-987
    CrossrefPubMedGoogle Scholar
  • 7 Gooriah R, Fayyaz A. Therapeutic uses of botulinum toxin. J Clin Toxicol 2015; 5 (01) 1-7
    PubMedGoogle Scholar
  • 8 Adler CH, Zimmerman RS, Lyons MK, Simeone F, Brin MF. Perioperative use of botulinum toxin for movement disorder-induced cervical spine disease. Mov Disord 1996; 11 (01) 79-81
    CrossrefPubMedGoogle Scholar
  • 9 Traynelis VC, Ryken T, Rodnitzky RL, Menezes AH. Botulinum toxin enhancement of postoperative immobilization in patients with cervical dystonia. Technical note. J Neurosurg 1992; 77 (05) 808-809
    CrossrefPubMedGoogle Scholar
  • 10 Iwamuro H, Takahashi H, Ide K, Nakauchi J, Taniguchi M. [Peri-operative treatment with botulinum A toxin prior to posterior cervical decompression in a case with cervical spondylosis caused by spasmodic torticollis secondary to cerebral palsy]. No Shinkei Geka 2003; 31 (09) 1015-1020
    PubMedGoogle Scholar
  • 11 Kim KN, Ahn PG, Ryu MJ. et al. Long-term surgical outcomes of cervical myelopathy with athetoid cerebral palsy. Eur Spine J 2014; 23 (07) 1464-1471
    CrossrefPubMedGoogle Scholar
  • 12 Furuya T, Yamazaki M, Okawa A. et al. Cervical myelopathy in patients with athetoid cerebral palsy. Spine 2013; 38 (03) E151-E157
    CrossrefPubMedGoogle Scholar
  • 13 Racette BA, Lauryssen C, Perlmutter JS. Preoperative treatment with botulinum toxin to facilitate cervical fusion in dystonic cerebral palsy. Report of two cases. J Neurosurg 1998; 88 (02) 328-330
    CrossrefPubMedGoogle Scholar
  • 14 Takemoto M, Ikenaga M, Tanaka C, Sonobe M, Shikata J. Cervical dystonia induced by cervical spine surgery: a case report. Spine 2006; 31 (01) E31-E34
    CrossrefPubMedGoogle Scholar
  • 15 Escher CM, Paracka L, Dressler D, Kollewe K. Botulinum toxin in the management of chronic migraine: clinical evidence and experience. Ther Adv Neurol Disorder 2017; 10 (02) 127-135
    CrossrefPubMedGoogle Scholar
  • 16 Rahimizadeh A, Soufiani HF, Rahimizadeh S. Cervical spondylotic myelopathy secondary to dropped head syndrome: report of a case and review of the literature. Case Rep Orthop 2016; 2016: 5247102
    PubMedGoogle Scholar