CC BY-NC-ND 4.0 · Thorac Cardiovasc Surg Rep 2020; 09(01): e33-e36
DOI: 10.1055/s-0040-1714075
Case Report: Thoracic

Myasthenia Gravis Related to Thymic Carcinoma: A Case Study

1  Neurology Departament, Hospital Santa Marcelina, Sao Paulo, São Paulo, Brazil
,
Samila Marissa Pinheiro Gomes
1  Neurology Departament, Hospital Santa Marcelina, Sao Paulo, São Paulo, Brazil
,
Sheila Aparecida Coelho Siqueira
2  Pathology Departament, Universidade de Sao Paulo Hospital das Clinicas, Sao Paulo, São Paulo, Brazil
,
Fernando Pereira Frassetto
2  Pathology Departament, Universidade de Sao Paulo Hospital das Clinicas, Sao Paulo, São Paulo, Brazil
,
Pedro Henrique Martins Arruda Sampaio
1  Neurology Departament, Hospital Santa Marcelina, Sao Paulo, São Paulo, Brazil
,
Cristiane Araujo Martins Moreno
1  Neurology Departament, Hospital Santa Marcelina, Sao Paulo, São Paulo, Brazil
3  Neurology Departament, Universidade de Sao Paulo Hospital das Clinicas, Sao Paulo, São Paulo, Brazil
,
Maria Sheila Guimarães Rocha
1  Neurology Departament, Hospital Santa Marcelina, Sao Paulo, São Paulo, Brazil
4  Neurology Departament, Faculdade Santa Marcelina Curso de Medicina, Sao Paulo, Sao Paulo, Brazil
,
Eduardo Paula Estephan
1  Neurology Departament, Hospital Santa Marcelina, Sao Paulo, São Paulo, Brazil
5  Neurology Departament, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, São Paulo, Brazil
› Author Affiliations
  

Abstract

Myasthenia gravis and thymoma are often presented in association with ∼10% of myasthenic cases having concomitant thymoma. Thymic carcinoma is one of the rarest/aggressive human epithelial tumors and has no correlation with myasthenia gravis hitherto. Here is provided a clinical case and review of literature on a very rare association of thymic carcinoma (with no sign of thymoma) and myasthenia gravis (antiacetylcholine receptor antibody positive). Two years after thymectomy, clinical evolution was satisfactory. This clinical case elicits hypothesis that thymic carcinoma may be related with myasthenia gravis, what may have good prognostic from oncologic and neurologic perspectives.



Publication History

Received: 12 March 2020

Accepted: 06 May 2020

Publication Date:
18 September 2020 (online)

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Georg Thieme Verlag KG
Stuttgart · New York