CC BY-NC-ND 4.0 · Eur J Dent 2020; 14(04): 575-583
DOI: 10.1055/s-0040-1713956
Original Article

Effect of Hydrogel-Based Antibiotic Intracanal Medicaments on Push-Out Bond Strength

Rayan B. Yaghmoor
1  Department of Restorative Dentistry, College of Dental Medicine, Umm Al-Qura university, Makkah, Saudi Arabia
2  Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, Indiana, United States
,
Jeffrey A. Platt
2  Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, Indiana, United States
,
Kenneth J. Spolnik
3  Department of Endodontics, Indiana University School of Dentistry, Indianapolis, Indiana, United States
,
Tien Min Gabriel Chu
2  Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, Indiana, United States
,
Ghaeth H. Yassen
2  Department of Biomedical Sciences and Comprehensive Care, Indiana University School of Dentistry, Indianapolis, Indiana, United States
4  Department of Endodontics, Case School of Dental Medicine, Cleveland, Ohio, United States
› Author Affiliations
Funding This study received its financial support from Delta Dental Foundation.

Abstract

Objective This study aimed to evaluate the effects of typical clinical concentration (1,000 mg/mL), low concentration (1 mg/mL) triple antibiotic pastes (TAP), and double antibiotic pastes (DAP) on the bond strength between various root cements and radicular dentin.

Materials and Methods Intact single-rooted human teeth (n = 144) were horizontally decoronated and canals instrumented. The roots were treated for 4 weeks with Ca(OH)2, 1,000 mg/mL of TAP or DAP, and 1 mg/mL of TAP or DAP. Untreated roots served as a control. After treatment, the medicaments were irrigated and each group was divided into three subgroups receiving MTA, Biodentine, or Endosequence putty cement. After 2 weeks, coronal and middle root cylinders were obtained from each root. Push-out bond strength test and failure analysis were performed for all root cylinders.

Statistical Analysis  Three-way ANOVA, pairwise comparisons and logistic regression were used for statistical analyses. A significance level of 5% was used.

Results  For MTA applied in the coronal part of the roots, 1 mg/mL DAP and TAP and Ca(OH)2 demonstrated significantly higher bond strength compared with the typical clinical concentration and the control groups. For Biodentine applied coronally in the roots, 1 mg/mL of DAP resulted in significantly higher bond strength than all other groups. For Endosequence putty cement applied coronally in the roots, 1 mg/mL of DAP offered significantly higher bond strength than all groups except for Ca(OH)2.

Conclusion The use of 1 mg/mL DAP resulted in significantly higher push-out bond strength compared with the typical clinical concentration of TAP and DAP regardless of the type of the root cement used.



Publication History

Publication Date:
29 July 2020 (online)

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