CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci 2020; 56(04): 231-233
DOI: 10.1055/s-0040-1713184
Case Report

Unilateral Dyshidrosiform Pemphigus Vulgaris

Manju Daroach
1   Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Dipankar De
1   Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Sanjeev Handa
1   Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Rahul Mahajan
1   Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Vikarn Vishwajeet
2   Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Uma N. Saikia
2   Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Author Affiliations

Abstarct

Pemphigus vulgaris is an autoimmune disease characterized by fluid-filled blisters over body and mucosal surfaces. Localized pemphigus is a rare presentation of the disease. There are few reports of localized pemphigus in literature presenting as esophageal involvement, recurrent paronychia, conjunctival mass, foot ulcers, discoloration of toes with hyperkeratotic skin lesions, verrucous lesions, and dyshidrosiform pemphigus vulgaris. We present a case of dyshidrosiform pemphigus involving a foot following trauma. Histopathology and direct immunofluorescence confirmed our diagnosis. In our patient, the disease started as localized dyshidrosiform pemphigus and later became generalized. This unusual presentation led to a delay in diagnosis and proper treatment in this patient. Physicians should be aware of such rare presentations to aid in the timely diagnosis and management of such patients.



Publication History

Article published online:
10 June 2020

© 2020. National Academy of Medical Sciences (India). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Michelerio A, Croci GA, Vassallo C, Brazzelli V. Hemorrhagic vesiculobullous eruption on the palms and the soles as presentation of dyshidrosiform bullous pemphigoid. JAAD Case Rep 2017; 4 (01) 61-63
  • 2 Gharami RC, Kumar P, Mondal A, Ghosh K. Dyshidrosiform Pemphigus vulgaris: report of an unusual case. Dermatol Online J 2010; 16 (07) 10
  • 3 Vaishnani JB, Bosamiya SS. Pemphigus: active or inactive?. Indian J Dermatol 2009; 54 (02) 186-188
  • 4 Levine N, Freilich A, Barland P. Localized pemphigoid simulating dyshidrosiform dermatitis. Arch Dermatol 1979; 115 (03) 320-321
  • 5 Shi CR, Charrow A, Granter SR, Christakis A, Wei EX. Unilateral, localized bullous pemphigoid in a patient with chronic venous stasis. JAAD Case Rep 2018; 4 (02) 162-164
  • 6 Lupi F, Masini C, Ruffelli M, Puddu P, Cianchini G. Dyshidrosiform palmoplantar pemphigoid in a young man: response to dapsone. Acta Derm Venereol 2010; 90 (01) 80-81
  • 7 Borradori L, Harms M. Podopompholyx due to pemphigus vulgaris and Trichophyton rubrum infection. Report of an unusual case. Mycoses 1994; 37 (3-4) 137-139