Severe Diabetic Ketoacidosis in a Child with Type-1 Diabetes, Asthma, and COVID-19

Wilson A. Vasconez; Carmen L. Bustamante Escobar; Nisha Agarwal; Juan P. Solano; Janine E. Sanchez

doi:10.1055/s-0040-1713164

Journal of Pediatric Intensive Care, Table of Contents

J Pediatr Intensive Care 2021; 10(03): 232-234
DOI: 10.1055/s-0040-1713164

Case Report

Severe Diabetic Ketoacidosis in a Child with Type-1 Diabetes, Asthma, and COVID-19

Wilson A. Vasconez

¹Department of Pediatrics, Holtz Children's Hospital/Jackson Memorial Health System, Miller School of Medicine, University of Miami, Miami, United States

,

Carmen L. Bustamante Escobar

¹Department of Pediatrics, Holtz Children's Hospital/Jackson Memorial Health System, Miller School of Medicine, University of Miami, Miami, United States

³Department of Pediatrics, Division of Pediatric Endocrinology, Miller School of Medicine, University of Miami, Miami, United States

,

Nisha Agarwal

¹Department of Pediatrics, Holtz Children's Hospital/Jackson Memorial Health System, Miller School of Medicine, University of Miami, Miami, United States

²Division of Pediatric Critical Care, Miller School of Medicine, University of Miami, Miami, United States

,

Juan P. Solano

¹Department of Pediatrics, Holtz Children's Hospital/Jackson Memorial Health System, Miller School of Medicine, University of Miami, Miami, United States

²Division of Pediatric Critical Care, Miller School of Medicine, University of Miami, Miami, United States

,

Janine E. Sanchez

¹Department of Pediatrics, Holtz Children's Hospital/Jackson Memorial Health System, Miller School of Medicine, University of Miami, Miami, United States

³Department of Pediatrics, Division of Pediatric Endocrinology, Miller School of Medicine, University of Miami, Miami, United States

› Author Affiliations

Abstract

Little is known about the association between novel coronavirus disease 2019 (COVID-19) and type-1 diabetes in children. A 16-year-old female patient with history of type-1 diabetes was admitted for life threatening diabetic ketoacidosis (DKA). She recovered from the DKA after 24 hours of insulin infusion and rehydration. On day 2, she was diagnosed with COVID-19. The DKA relapsed and required restarting insulin. She developed leukopenia, neutropenia, and high ferritin. Upon recovery, she was discharged for self-quarantine. Severity of DKA in children with COVID-19 is multifactorial. Clinical suspicion of COVID should be heightened in patients who present with unexplainedly severe DKA.

Keywords

COVID-19 - diabetic ketoacidosis - type-1 diabetes

Full Text

References

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