COVID-19 Pandemic and Role of Human Saliva as a Testing Biofluid in Point-of-Care Technology

Hiba Hamid; Zohaib Khurshid; Necdet Adanir; Muhammad S. Zafar; Sana Zohaib

doi:10.1055/s-0040-1713020

European Journal of Dentistry, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Eur J Dent 2020; 14(S 01): S123-S129
DOI: 10.1055/s-0040-1713020

Review Article

COVID-19 Pandemic and Role of Human Saliva as a Testing Biofluid in Point-of-Care Technology

Authors

Hiba Hamid

¹Department of Oral Biology, Liaquat College of Medicine and Dentistry, Karachi, Pakistan
Zohaib Khurshid

²Department of Prosthodontics and Dental Implantology, College of Dentistry, King Faisal University, Al Ahsa, Saudi Arabia
Necdet Adanir

³Department of Restorative Dentistry, College of Dentistry, King Faisal University, Al Ahsa, Saudi Arabia
Muhammad S. Zafar

⁴Department of Restorative Dentistry, College of Dentistry, Taibah University, Medina Munawara, Saudi Arabia

⁵Department of Dental Materials, Islamic International Dental College, Riphah International University, Islamabad, Pakistan
Sana Zohaib

⁶Department of Biomedical Engineering, College of Engineering, King Faisal University, Al Ahsa, Saudi Arabia

Abstract

Novel coronavirus disease 2019 (COVID-19) outbreak has termed as a controllable pandemic, and the entire world has come to a standstill trying to mitigate the disease with health systems. Health care providers, around the globe, are fighting day and night. Currently, rapid testing is taking place with the help of nasopharyngeal, oropharyngeal swab, bronchoalveolar lavage, sputum, urine, and blood. All these approaches are invasive or embarrassing to the infected person. It is observed that salivary glands are hosting severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) because of angiotensin-converting enzyme 2 and the detection of high viral loads in the saliva and is playing a crucial role in virus transmission, especially from individuals showing absolutely no symptoms. Saliva is proving to be a promising noninvasive sample specimen for the diagnosis of COVID-19, thus helping to monitor the infection and prevent it from further spreading by prompt isolation.

Keywords

saliva - COVID-19 - SARS-CoV-2 - testing - point of care - virus

Volltext

Referenzen

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