Impact of Microwave Ablation Treatment on the Biomechanical Properties of the Distal Canine Radius: A Cadaveric Study

Introduction: Ablative techniques, such as microwave ablation (MWA), have recently emerged as promising therapeutic approaches to local tumor control. MWA is a minimally invasive ablative therapy that was recently reported for treatment of primary bone malignancies in people. The objective of this study was to determine if MWA treatment modifies the biomechanics properties of the normal canine distal radius.

Materials and Methods: Sixteen pairs of forelimbs from skeletally mature mixed breed canine cadavers were used. For each cadaver, one radius was assigned to the MWA group and the other to the control group. A 2-mm diameter bone tunnel was created in both groups extending 6 cm proximally from the distal articular surface. MWA was performed on those designated to this group. Specimens were tested in three-point bending, with the middle point located 3 cm from the distal articular surface (middle of ablated zone). Load and displacement were continuously recorded to allow for determination of ultimate strength and yield points.

Results: The mean peak load for the control group and the MWA group was 1641.9 and 1590.9 N, respectively. These results indicate that MWA radii are not substantially inferior to controls (peak load ratio p < 0.0001).

Discussion/Conclusion: This study looked at the biomechanics of the normal cadaveric radii treated with MWA. Application of MWA on osteosarcoma affected radii might affect the biomechanics differently. Future studies are needed to further evaluate MWA treatment of neoplastic bone lesions.

Acknowledgment: There was no proprietary interest or funding provided for this project.